Protein Alignment TMED5 and eca

DIOPT Version :10

• Sequence 1: NP_057124.3
• Gene: TMED5 / 50999
• HGNCID: 24251
• Length: 229
• Species: Homo sapiens
• Sequence 2: NP_788616.1
• Gene: eca / 41177
• FlyBaseID: FBgn0069242
• Length: 216
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 48/209 - (22%)
• Similarity: 90/209 - (43%)
• Gaps: 38/209 - (18%)

Human    38 FTLPAGQKECFYQPMPLKASLEIEYQV-------------LDGAGLDIDFHLASPEGKTLVFEQR 89
            |.:...:::||.:.:|.:.::.:.|:|             ..|.|:.::  :...:.|.::....
  Fly    23 FHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVE--VRDSDDKIVLSRVY 85

Human    90 KSDG-----VHTVETEVGDYMFC-FDNTFSTISEKVIFFELILDNMGEQAQEQED--WKKYITGT 146
            .|.|     .||    .|:::.| |.|:.:..|...:...|.: .:||.|.:...  .|:.:|.
  Fly    86 SSQGRISFTSHT----PGEHVICMFSNSTAWFSGAQLRVHLDI-QVGEHAIDYAHVAQKEKLTE- 144

Human   147 DILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVSA 211
              |.:::..:|:.:..|...       |...|..|.|.|:..||...||.:||:...||:|.:..
  Fly   145 --LQLRIRQLLDQVEQITKE-------QNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGF 200

Human   212 IQVYMLKSLFEDKR 225
            .|:..|||.||.|:
  Fly   201 WQMRHLKSFFEAKK 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMED5	NP_057124.3	EMP24_GP25L	35..222	CDD:426051	45/204 (22%)
eca	NP_788616.1	EMP24_GP25L	20..211	CDD:426051	45/204 (22%)