Protein Alignment TMED5 and opm

DIOPT Version :10

• Sequence 1: NP_057124.3
• Gene: TMED5 / 50999
• HGNCID: 24251
• Length: 229
• Species: Homo sapiens
• Sequence 2: NP_572994.1
• Gene: opm / 32435
• FlyBaseID: FBgn0264389
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 225
• Identity: 93/225 - (41%)
• Similarity: 135/225 - (60%)
• Gaps: 9/225 - (4%)

Human     5 IWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDG-- 67
            |||..|.|:|......||.|... ..:.|.:.|..:.||:.||.|..:....:::.||||:||
  Fly     4 IWLGMPGLVLLLSIAALLLGVQD-AEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGH 67

Human    68 AGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKVIFFELILDNMGE 131
            ..|||.|.|..|.|..:|.:.:|.:.||..| .:.|||.|||||:||..:.|.:|||||::..||
  Fly    68 GDLDISFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGE 132

Human   132 QAQEQEDWKK--YITG---TDILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESN 191
            :.|....|.:  .:||   .:..|||::||::.|..|:.:|:|:..:|.:||:.||||||:.|||
  Fly   133 ELQGDTQWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESN 197

Human   192 FDRVNFWSMVNLVVMVVVSAIQVYMLKSLF 221
            |.:||.||||.:..|:.|..|||:||:|:|
  Fly   198 FQKVNHWSMVQISAMIGVGLIQVFMLRSIF 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMED5	NP_057124.3	EMP24_GP25L	35..222	CDD:426051	83/195 (43%)
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:426051	82/193 (42%)