Protein Alignment TMED5 and CG31787

DIOPT Version :10

• Sequence 1: NP_057124.3
• Gene: TMED5 / 50999
• HGNCID: 24251
• Length: 229
• Species: Homo sapiens
• Sequence 2: NP_724105.1
• Gene: CG31787 / 318941
• FlyBaseID: FBgn0051787
• Length: 232
• Species: Drosophila melanogaster
• Alignment Length: 231
• Identity: 76/231 - (32%)
• Similarity: 117/231 - (50%)
• Gaps: 33/231 - (14%)

Human     5 IWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLP----------AGQKECFYQPMPLKASLE 59
            ||| ..:|||                 ||..|:...|          ||::||||||:....:::
  Fly     8 IWL-LQLLLL-----------------LDLKFSNAEPHNKQLTVFAEAGRQECFYQPIATTENIK 54

Human    60 IEYQVLDGAGL---DIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKVI 120
            |:|||:.| ||   .|:|:|..|..:.|:.|.::..|.|::: .|.|.|.||||||.||.::|::
  Fly    55 IDYQVIHG-GLGETHINFNLMDPSRRLLIAETKRQMGKHSIQANETGSYKFCFDNTISTFNQKIV 118

Human   121 FFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDR 185
            .|.|.:.....:.:|..|.::.:......|:....|...:..|...|.:|...|..:||.|||||
  Fly   119 SFTLEVAPADREERELRDLRQEMLTDYHFDVAYTGIDSYVGKIHVNLMRSRQTQDFIRAIEARDR 183

Human   186 NIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLF 221
            |:.||.:..||.||....:.|:.|..:||.|::|:|
  Fly   184 NVAESTYSMVNKWSWAQFLSMIFVGFLQVLMVRSIF 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMED5	NP_057124.3	EMP24_GP25L	35..222	CDD:426051	68/201 (34%)
CG31787	NP_724105.1	EMP24_GP25L	31..220	CDD:426051	66/190 (35%)