Protein Alignment TMED5 and CHOp24

DIOPT Version :10

• Sequence 1: NP_057124.3
• Gene: TMED5 / 50999
• HGNCID: 24251
• Length: 229
• Species: Homo sapiens
• Sequence 2: NP_572165.1
• Gene: CHOp24 / 31382
• FlyBaseID: FBgn0029709
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 220
• Identity: 59/220 - (26%)
• Similarity: 105/220 - (47%)
• Gaps: 26/220 - (11%)

Human    11 VLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDIDFH 75
            ||||.....:|...:..|..|:|        |..:|||::.:.......:.::|:||..||:|..
  Fly     8 VLLLVGSLLILCRTSHAFIVSVD--------AHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIK 64

Human    76 LASPEGKTLVFEQRKSDGVHT-VETEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQAQ----E 135
            ::.|:...:...:::|.|.:| |....|.|..||:|..|:::.|::.|.:.:.:..::|.    |
  Fly    65 ISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSIDVGDAPQRAPGAPGE 129

Human   136 QEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSM 200
            :|          :...||||:   |..:...|:...|.|..:...:...|::.|:...||..||.
  Fly   130 EE----------VGHTKLEDM---IRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWST 181

Human   201 VNLVVMVVVSAIQVYMLKSLFEDKR 225
            ...:|:|:::..|||.||..||.||
  Fly   182 FEALVLVLMTVGQVYYLKRFFEVKR 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMED5	NP_057124.3	EMP24_GP25L	35..222	CDD:426051	47/191 (25%)
CHOp24	NP_572165.1	EMP24_GP25L	24..203	CDD:426051	50/199 (25%)