Protein Alignment TBX22 and tbx22

DIOPT Version :10

• Sequence 1: NP_058650.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Sequence 2: XP_005157203.1
• Gene: tbx22 / 556143
• ZFINID: ZDB-GENE-090626-2
• Length: 444
• Species: Danio rerio
• Alignment Length: 499
• Identity: 215/499 - (43%)
• Similarity: 283/499 - (56%)
• Gaps: 97/499 - (19%)

Human     5 SRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTS 69
            :|.:...||    ......|||.::.:...||...  .:.::.|.||.      |::|
Zfish    14 NRCKKMKVE----NRENESLQDVLEYDSDTLRRTL--FDAQDLRKSAK------ERKP------- 59

Human    70 ASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDP 134
                .|:::          .:.::::||||:|||||::|||||||||.|||||||:||||..|||
Zfish    60 ----AGAEA----------VRKVRVDLQGSDLWKRFYEIGTEMIITKVGRRMFPSIRVKVHNLDP 110

Human   135 GKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRM 199
            .:||.:|:|::|:|||:||||||||||::||||||.||.|..|||||||||||.||||:|||||:
Zfish   111 LQQYSIAMDIMPMDSKKYRYVYHSSQWVIAGNTDHSCIPPHLYVHPDSPCSGENWMRQVISFDRV 175

Human   200 KLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLS-QIQSLPTEGVKTFSFKETEFTTVTAYQ 263
            ||||||:||:|||||:|||||:||:|||.......|| ::.|||.:||.||||.||:||||||||
Zfish   176 KLTNNELDDRGHIILKSMHKYRPRIHVILHCPPECLSKRLLSLPADGVFTFSFPETQFTTVTAYQ 240

Human   264 NQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQ-----SGSSGSS 323
            |||||||||:|||||||||:  ||..||||:||:|.|...|. .||:...:.|     |.:||.:
Zfish   241 NQQITKLKIDRNPFAKGFRE--RNGAVLDGILESYSWHSPFN-GFKSLAMELQGRCFGSSASGIT 302

Human   324 PVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVL 388
            |..||..|..| .:..||.|..   .||:|     |..||     ...| .||..|:...:|
Zfish   303 PSVSSAQAVHP-TAFSSPQCCK---ILPSS-----CFLAY-----RAYC-SICLNNYTGLRP--- 349

Human   389 PAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQM---LYGLQSP 450
                              |:::|:|:||.|   |.|....|...|..|..|.:.:   |.|..|
Zfish   350 ------------------MLDLPLLTSLPV---KKGDRCRSHWLYNSAGTSMHPIHNTLSGWAS- 392

Human   451 GNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKV 494
                 .|..|..|....       :.|:|.:..|..:.::|||:
Zfish   393 -----ENENTASAFMSP-------HSYSFPISHRFSTDTHHLKL 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX22	NP_058650.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		14/85 (16%)
		T-box_TBX22-like	90..283	CDD:410326	140/193 (73%)
tbx22	XP_005157203.1	T-box	66..260	CDD:469628	140/193 (73%)