Protein Alignment TBX22 and tbx-40

DIOPT Version :9

• Sequence 1: NP_001103348.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_502852.1
• Gene: tbx-40 / 190679
• WormBaseID: WBGene00006559
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 98/451 - (21%)
• Similarity: 167/451 - (37%)
• Gaps: 97/451 - (21%)

Human    87 LEEKDIQMELQGSELWKRFHDIGTEMIITKAG-RRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSK 150
            :::....:::...:.|...:. ..|||:...| :.:||.:...:.||:...:|.|.:.:...|:
 Worm     2 IQQAQFNVQMAEEDRWLTQYP-NMEMIVNNKGPKPIFPELNFNITGLEEKSRYVVLLSIQKFDN- 64

Human   151 RYRYVYHSSQW---MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE--MDDKG 210
             .||.:.:.:|   .|...|.....| ::::|||....||..|::.|.||.:::||::  ||...
 Worm    65 -IRYGFKNGKWGPSKVRHATKKEQEI-KYFLHPDGTKLGEELMKETIKFDTVRITNHKKFMDKDN 127

Human   211 HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQI--TKLKIE 273
            ...:::||||.|.:.|      .:::.::|    ...:...:..:|..||.|..:.|  .|.|..
 Worm   128 VFFVETMHKYVPVLTV------KNITNVES----ANHSMRMEVAQFFPVTVYNQESIGNWKSKFH 182

Human   274 RNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFG-ADTQSGSSGSSPVTSSGGAPSPLNS 337
            :|...:...|.|..|...:...|....|.....:..... ....|.|...:..|:||...:.::
 Worm   183 KNATFENRLDGGNKRKNTNSREEPSSKRSKNETEIAVLDILQVASQSENYNESTNSGRLQNEIS- 246

Human   338 LLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQS 402
                   |.:...|::|.....|.|| |.||.|..|.       ||.|......:......:.::
 Worm   247 -------SSIHQFPSTSYQNQYPHAY-PTVNTPPIYA-------QQFPAPFDEKQNQFYPKTDEN 296

Human   403 LAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCS 467
            |||                  ..::|:|    ..||               |..|.....|....
 Worm   297 LAP------------------NCAQDAS----SLPN---------------FAMNQKASFANQYP 324

Human   468 FHPSYDFYRYNFSMPSRLISGSNHL----KVNDDS--QVSFG--------EGKCNHVHWYP 514
            :||.|..|       |:|..||.:.    .:|.||  |.||.        .|...|..:||
 Worm   325 YHPYYHQY-------SQLDHGSPYQYMNNSINSDSSFQSSFSTENSYFDDNGNPIHYPYYP 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX22	NP_001103348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		0/3 (0%)
		TBOX	91..287	CDD:238106	48/203 (24%)
tbx-40	NP_502852.1	T-box	24..186	CDD:279278	45/174 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161449162
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840