Protein Alignment TBX22 and tbx-8

DIOPT Version :9

• Sequence 1: NP_001103348.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_499287.2
• Gene: tbx-8 / 176450
• WormBaseID: WBGene00006545
• Length: 315
• Species: Caenorhabditis elegans
• Alignment Length: 339
• Identity: 106/339 - (31%)
• Similarity: 147/339 - (43%)
• Gaps: 84/339 - (24%)

Human    88 EEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRY 152
            |::|        :||..||....|||:||:||:|||.:...|:||.|.|.|.:.:.:.|.|..||
 Worm    11 EDQD--------KLWNLFHYHKNEMIVTKSGRKMFPKLEYVVRGLTPNKLYAMMLHIEPSDDHRY 67

Human   153 RYVYHSSQWMVAGNTD-HLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTN-NEMDDKGHIILQ 215
            :  :.|.:|:.:|..: |.  .|:...|.|...||:.||...:.|||:|:|| .|..:...|.|.
 Worm    68 K--FSSGEWVKSGKAEKHR--EPKKLWHADGVRSGKEWMTNPVCFDRVKITNCAESTNASMIFLH 128

Human   216 SMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKG 280
            |||||.|.:.:.|..|....| :....|..|.:.....|||..||||||..:.||||:.||||||
 Worm   129 SMHKYTPVMSIYESPSESPFS-VPQPSTRLVTSVRLTYTEFIAVTAYQNDAVIKLKIKFNPFAKG 192

Human   281 FRD---TGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPL 342
            ||:   :.|.|.           .||         ||..:....||.|:|    |.|..|  ..:
 Worm   193 FREGSQSDRKRN-----------SPS---------ADDSTTDESSSQVSS----PQPKKS--RTV 231

Human   343 CFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLM 407
            ..||                       ||..:|.||        ::|.|         .::.||.
 Worm   232 SVSP-----------------------PLMPRILPT--------MIPPP---------PAINPLF 256

Human   408 MEVPMLSSLGVTNS 421
            ..:|..|.|..|.:
 Worm   257 YSLPYFSHLAATGN 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX22	NP_001103348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		1/2 (50%)
		TBOX	91..287	CDD:238106	77/200 (39%)
tbx-8	NP_499287.2	TBOX	4..199	CDD:238106	78/200 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161449159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840