DRSC/TRiP Functional Genomics Resources

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Protein Alignment NTM and opcml

DIOPT Version :10

Sequence 1:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:360 Identity:188/360 - (52%)
Similarity:247/360 - (68%) Gaps:30/360 - (8%)


- Green bases have known domain annotations that are detailed below.


Human    12 ISWAIFTGLAALCLF---QGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRST 73
            :.|.....:|...||   .|||.||||:..   .||:|||||:||.|:|::||:|:|||||||:|
Zfish     9 LQWKCLVVVALRLLFLVPAGVPARSGDSYL---KDNITVRQGDSAVLKCSMDNKVSRVAWLNRTT 70

Human    74 ILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKI 138
            ||:.||:||.||||||||:....:|||:|.||::||||||.||:.|:..|::::|||||||..:|
Zfish    71 ILFTGNEKWSLDPRVVLLNTAVNEYSIKILNVNLYDEGPYVCSILTNKKPESTKVHLIVQVPARI 135

Human   139 VEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSA 203
            |.:|:|:|:|||:|:||.|:|.|||||::.|:..|.|....|:|.||:|:.|||::.||.|:|..
Zfish   136 VNVSTDVSVNEGSNVSLMCLAIGRPEPSILWKFRSSKGNRIVTEGEYVEMTGITKDMSGSYDCIT 200

Human   204 SNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKG 268
            |||::.|.||.|:|||||||.||.|:.||..|||||.|.|||||||.|:|||:|.::|::.|..|
Zfish   201 SNDISPPDVRTVQVTVNYPPVISRARSTGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNG 265

Human   269 VKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPW 333
            ||:||:...|.|.||||||.|||||||||.|.||.|||||:|:                      
Zfish   266 VKIENKGKQSMLTFFNVSEEDYGNYTCVAINTLGITNASIILY---------------------- 308

Human   334 KGPGAVSEVSNGT-SRRAGCVWLLPLLVLHLLLKF 367
             ||||:.:|:|.. |.....:.|..||.|.||.||
Zfish   309 -GPGAIHDVNNAALSPTCSLLLLTLLLTLSLLSKF 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NTMNP_001338930.1 Ig 44..132 CDD:472250 54/87 (62%)
Ig strand B 53..57 CDD:409353 2/3 (67%)
Ig strand C 65..69 CDD:409353 3/3 (100%)
Ig strand E 98..102 CDD:409353 3/3 (100%)
Ig strand F 112..117 CDD:409353 3/4 (75%)
Ig strand G 125..128 CDD:409353 0/2 (0%)
Ig_3 136..205 CDD:464046 33/68 (49%)
Ig 223..307 CDD:472250 53/83 (64%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 2/3 (67%)
Ig strand E 278..282 CDD:409353 2/3 (67%)
Ig strand F 292..297 CDD:409353 4/4 (100%)
opcmlNP_001005580.1 Ig 41..129 CDD:472250 54/87 (62%)
Ig strand B 50..54 CDD:409353 2/3 (67%)
Ig strand C 62..66 CDD:409353 3/3 (100%)
Ig strand E 95..99 CDD:409353 3/3 (100%)
Ig strand F 109..114 CDD:409353 3/4 (75%)
Ig strand G 122..125 CDD:409353 0/2 (0%)
Ig 128..214 CDD:472250 44/85 (52%)
Ig strand B 150..154 CDD:409353 2/3 (67%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand E 181..185 CDD:409353 2/3 (67%)
Ig strand F 195..200 CDD:409353 2/4 (50%)
Ig 220..308 CDD:472250 56/87 (64%)
Ig strand B 236..240 CDD:409353 2/3 (67%)
Ig strand C 249..253 CDD:409353 2/3 (67%)
Ig strand E 275..279 CDD:409353 2/3 (67%)
Ig strand F 289..294 CDD:409353 4/4 (100%)
Ig strand G 302..305 CDD:409353 2/2 (100%)

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