Protein Alignment PARD6A and par-6

DIOPT Version :9

• Sequence 1: XP_005256034.1
• Gene: PARD6A / 50855
• HGNCID: 15943
• Length: 357
• Species: Homo sapiens
• Sequence 2: NP_001040687.1
• Gene: par-6 / 173137
• WormBaseID: WBGene00003921
• Length: 309
• Species: Caenorhabditis elegans
• Alignment Length: 311
• Identity: 159/311 - (51%)
• Similarity: 199/311 - (63%)
• Gaps: 31/311 - (9%)

Human    14 SIVEVKSKFDAEFRRFALPRASVSG--FQEFSRLLRAVHQIPGLDVLLGYTDAHGDLLPLTNDDS 76
            |.::||||||:|:|||::|..|.||  :..|..|:..:|.:..:...|.|....|||||:||||:
 Worm    13 STLQVKSKFDSEWRRFSIPMHSASGVSYDGFRSLVEKLHHLESVQFTLCYNSTGGDLLPITNDDN 77

Human    77 LHRALASGPPPLRLLVQKRGEEGYSGQPLWAEADSSGLAFASNSLQRRKKGL--LLRPVAPLRTR 139
            |.::..|..|.||||:|:|||.       |.|....|     ....:|.||:  |:....|.|:
 Worm    78 LRKSFESARPLLRLLIQRRGES-------WEEKYGYG-----TDSDKRWKGISSLMAQKPPKRS- 129

Human   140 PPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIF 204
              ..||.|:||||||::||||::||.||||||.|||.:||||||||||.||||..:|:.:|.|||
 Worm   130 --YSISNPEDFRQVSAIIDVDIVPEAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIF 192

Human   205 ISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRNNVVRG 269
            |||||.||||||||||.|:||:||||||||.||||||||||||||:||||:|||||||||.:.||
 Worm   193 ISRLVDGGLAESTGLLGVNDEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQRNTLSRG 257

Human   270 ASGRLTGPPSAGPGPAEPDSDDDSSDLVIENRQPPSSNGLSQGPPCWDLHP 320
            .|.:  |.|:|....|...:.....      ::|...||.|.|    ..||
 Worm   258 PSQQ--GTPNASEMSAATAAATGGI------QRPMKMNGSSDG----SYHP 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARD6A	XP_005256034.1	PB1_Par6	16..95	CDD:99724	36/80 (45%)
		PDZ_signaling	167..258	CDD:238492	72/90 (80%)
par-6	NP_001040687.1	PB1_Par6	15..96	CDD:99724	36/80 (45%)
		PDZ_signaling	155..246	CDD:238492	72/90 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161460463
Domainoid	1	1.000	120	1.000	Domainoid score	I3935
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2055
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D356104at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm15281
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5019
SonicParanoid	1	1.000	-	-		X1143
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.030