DRSC/TRiP Functional Genomics Resources

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Protein Alignment F11R and dpr12

DIOPT Version :10

Sequence 1:NP_001369656.1 Gene:F11R / 50848 HGNCID:14685 Length:327 Species:Homo sapiens
Sequence 2:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster


Alignment Length:255 Identity:58/255 - (22%)
Similarity:85/255 - (33%) Gaps:80/255 - (31%)


- Green bases have known domain annotations that are detailed below.


Human    48 LSCAYSGFSSPRVEWK----FDQGD----TTRLVCYNNKITASYEDRVTFLPT------GITFKS 98
            |.|..||.....|.|.    ..:.|    ::....|.|      ::|...|.|      .:..|.
  Fly    97 LVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTN------DERFAILHTPGSNMWTLQIKF 155

Human    99 VTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATI----GNRAVLTC-SEQDG 158
            |.|.|.|.|.|.||...|.....|.::::|      |...|..|..:    |:...|.| .|:..
  Fly   156 VQRRDHGMYECQVSTPTGIISHFVNLQV
VV------PEAFILGSGELHVDMGSTINLVCIIEKSP 214

Human   159 SPPSEYTWFKD-----------GIVMPTNPKSTRAFSNSSYVLNP-TTGELVFDPLSASDTGEYS 211
            :||....|.|:           .|.:.|.|             .| |...|:......:|:|.|:
  Fly   215 TPPQYVYWQKNDRLINYVDSRRDITIETTP-------------GPRTQSRLIIREPQVTDSGNYT 266

Human   212 CEARN----------GYGTPM-------TSNAVRMEAVERNVGVIVAAVLVTLILLGILV 254
            |.|.|          ..|..|       ||:|.|:..:.|       ::|...:||..:|
  Fly   267 CSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTHIFR-------SMLAPCLLLNTVV 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
F11RNP_001369656.1 IgV_1_JAM1-like 30..129 CDD:409538 23/94 (24%)
FR1 30..52 CDD:409538 2/3 (67%)
Ig strand A 30..33 CDD:409538
Ig strand A' 37..41 CDD:409538
Ig strand B 44..53 CDD:409538 2/4 (50%)
CDR1 53..58 CDD:409538 2/4 (50%)
Ig strand C 58..66 CDD:409538 2/11 (18%)
FR2 59..66 CDD:409538 2/10 (20%)
CDR2 69..83 CDD:409538 2/13 (15%)
Ig strand C' 69..74 CDD:409538 0/4 (0%)
Ig strand C' 77..79 CDD:409538 1/1 (100%)
FR3 84..112 CDD:409538 10/33 (30%)
Ig strand D 86..90 CDD:409538 1/3 (33%)
Ig strand E 92..96 CDD:409538 1/9 (11%)
Ig strand F 105..113 CDD:409538 4/7 (57%)
CDR3 113..119 CDD:409538 1/5 (20%)
Ig strand G 119..128 CDD:409538 1/8 (13%)
FR4 120..129 CDD:409538 1/8 (13%)
IgI_2_JAM1 135..231 CDD:409542 29/129 (22%)
Ig strand A 135..139 CDD:409542 1/3 (33%)
Ig strand A' 141..144 CDD:409542 1/2 (50%)
Ig strand B 147..155 CDD:409542 2/8 (25%)
Ig strand C 163..168 CDD:409542 1/4 (25%)
Ig strand C' 170..172 CDD:409542 0/1 (0%)
Ig strand D 187..191 CDD:409542 0/3 (0%)
Ig strand E 195..199 CDD:409542 1/3 (33%)
Ig strand F 208..214 CDD:409542 3/5 (60%)
Ig strand G 221..231 CDD:409542 5/16 (31%)
dpr12NP_652462.3 IG_like 86..183 CDD:214653 23/91 (25%)
Ig strand B 95..99 CDD:409353 1/1 (100%)
Ig strand C 109..117 CDD:409353 2/7 (29%)
Ig strand E 149..153 CDD:409353 0/3 (0%)
Ig strand F 163..168 CDD:409353 2/4 (50%)
Ig strand G 176..179 CDD:409353 0/2 (0%)
Ig_3 195..271 CDD:464046 19/88 (22%)
Blue background indicates that the domain is not in the aligned region.

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