DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment F11R and beat-IIa

DIOPT Version :9

Sequence 1:	NP_001369656.1	Gene:	F11R / 50848	HGNCID:	14685	Length:	327	Species:	Homo sapiens
Sequence 2:	NP_001287375.1	Gene:	beat-IIa / 42086	FlyBaseID:	FBgn0038498	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	389	Identity:	78/389 - (20%)
Similarity:	129/389 - (33%)	Gaps:	104/389 - (26%)

- Green bases have known domain annotations that are detailed below.

Human    14 LFILAILLCSL-----ALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLV 73
            |.:|.:||.|:     ||.:|.:....|.||  ....|.|.|.|....:|....||.:|   :|.
  Fly    51 LLLLGVLLLSMELVECALRNVNLIIEPPAVR--RGQHVVLRCMYDLDGAPLYSAKFYRG---QLE 110

Human    74 CY--------NNKI---TASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGG--NSYGEVKVK 125
            .|        |.|:   ...:.|..:...|.:..::|....:|.::|.|:.:..  ::...|...
  Fly   111 FYRYTPGEFPNTKVFPFPGIHVDVSSSNATQVLLRNVGFGLSGNFSCEVTADAPLFSTATAVDTM 175

Human   126 LIVLVPPSKPTVNI------PSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMP---------- 174
            .:|.:|..:|.|..      |......|     ||.....|.:|.|:..:.:|:.
  Fly   176 QVVELPEKRPQVFTEHTRYEPGDVLRAN-----CSTPPSRPRAELTFTINNMVITHVDTEYIRTI 235

Human   175 TNPKSTR-----------------AFSNSSYVLNPTTGE--LVFDPLSASDTGEYSCEARNG--- 217
            .|..:||                 |..|:.|.||...|.  .|:.|.|........|.|:.|
  Fly   236 DNLIATRISLKMQLQGIHFSSVNPAIYNNVYGLNSVYGHGGPVYAPNSNPGGLLLRCSAQIGDLY 300

Human   218 -------YGTPMTSNAVRMEAVERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDKLGACPSI 275
                   .|||      :.:.|...|.:.....|...       |..:|:.|.....:|  .|.:
  Fly   301 QEYKEIELGTP------QKDPVPARVTLSSDTSLKNF-------FSSYFSTSASAASRL--LPGV 350

Human   276 FPS--------------HAVF--CPADTHDPISSLSGTKKGTSSKKVIYSQPSARSEGEFKQTS 323
            :.:              .|.|  |.|.:.||.|....:.:.:..::....:|:..|.....:.|
  Fly   351 YMAPLIMAMLASLFRLIEAAFEPCDASSQDPQSQTGHSMEHSKERREPKERPALVSSCSVSKAS 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F11R	NP_001369656.1	IgV_1_JAM1-like	30..129	CDD:409538	22/111 (20%)
		Ig strand B	46..50	CDD:409538	2/3 (67%)
		Ig strand C	59..63	CDD:409538	0/3 (0%)
		Ig strand E	92..96	CDD:409538	1/3 (33%)
		Ig strand F	106..111	CDD:409538	1/4 (25%)
		Ig strand G	121..124	CDD:409538	1/2 (50%)
		IgI_2_JAM1	135..231	CDD:409542	28/140 (20%)
		Ig strand B	149..153	CDD:409542	0/3 (0%)
		Ig strand C	163..167	CDD:409542	2/3 (67%)
		Ig strand E	195..199	CDD:409542	1/5 (20%)
		Ig strand F	209..214	CDD:409542	1/4 (25%)
		Ig strand G	224..227	CDD:409542	0/2 (0%)
beat-IIa	NP_001287375.1	PTZ00491	<209..>261	CDD:240439	7/51 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910