Protein Alignment F11R and lbk

DIOPT Version :9

• Sequence 1: NP_001369656.1
• Gene: F11R / 50848
• HGNCID: 14685
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 65/261 - (24%)
• Similarity: 104/261 - (39%)
• Gaps: 62/261 - (23%)

Human    28 SVTVHSSEPEVRIPEN------NPVKLSCAYSGFSSPRVE-WKFDQGDTTRLVCYNNKITASYED 85
            |:.:|.:  .:::|.|      ...:|.|:.||..:|.:. .||.          .::..|:.|.
  Fly   829 SIGIHPT--FLQVPSNLTLDAGEMARLVCSASGDPTPEIALQKFG----------GSEFPAATER 881

Human    86 RV-------TFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIP--- 140
            |:       .||.|     :....|:|.|||...    ::.||:||. ..||...||..:||
  Fly   882 RLQVIREENAFLIT-----NAKPSDSGIYTCTAL----SAAGEIKVN-ATLVVNDKPQPSIPLVH 936

Human   141 SSATIGNRAVLTCSEQDGSPPSEY-----TWFKDG---IVMPTNPKSTR-AFSNSSYVLNPTTGE 196
            ....:|...||.|..:..:...|.     .|||:.   .:.||.|...| .|||:..:
  Fly   937 QEVVVGRTCVLQCLSETANADFELEHPHREWFKENKPIHISPTAPDGDRYYFSNNKEL------- 994

Human   197 LVFDPLSASDTGEYSCEARNGYGT-PMTSNAVRMEAVERN---VGVIVAAVLVTLILLGILVFGI 257
            ||.....::|.|.:.||..:...| .:.|..|   .|:.|   |.::|..:.||:|.:.:....|
  Fly   995 LVILNAQSNDAGHFRCEITDNSRTFTLQSELV---VVKENLNWVVLLVGIITVTVICVVVDCCII 1056

Human   258 W 258
            |
  Fly  1057 W 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F11R	NP_001369656.1	IgV_1_JAM1-like	30..129	CDD:409538	25/112 (22%)
		Ig strand B	46..50	CDD:409538	1/3 (33%)
		Ig strand C	59..63	CDD:409538	0/4 (0%)
		Ig strand E	92..96	CDD:409538	1/3 (33%)
		Ig strand F	106..111	CDD:409538	3/4 (75%)
		Ig strand G	121..124	CDD:409538	1/2 (50%)
		IgI_2_JAM1	135..231	CDD:409542	27/108 (25%)
		Ig strand B	149..153	CDD:409542	2/3 (67%)
		Ig strand C	163..167	CDD:409542	1/8 (13%)
		Ig strand E	195..199	CDD:409542	1/3 (33%)
		Ig strand F	209..214	CDD:409542	1/4 (25%)
		Ig strand G	224..227	CDD:409542	1/2 (50%)
lbk	NP_611091.2	LRR_RI	<275..446	CDD:238064
		leucine-rich repeat	293..316	CDD:275380
		LRR_8	316..373	CDD:290566
		leucine-rich repeat	317..338	CDD:275380
		leucine-rich repeat	339..362	CDD:275380
		leucine-rich repeat	363..386	CDD:275380
		LRR_8	386..445	CDD:290566
		leucine-rich repeat	387..410	CDD:275380
		leucine-rich repeat	411..434	CDD:275380
		leucine-rich repeat	435..457	CDD:275380
		LRR_8	457..516	CDD:290566
		leucine-rich repeat	458..481	CDD:275380
		leucine-rich repeat	482..505	CDD:275380
		LRR_RI	<498..669	CDD:238064
		LRR_8	504..564	CDD:290566
		leucine-rich repeat	506..529	CDD:275380
		leucine-rich repeat	530..553	CDD:275380
		leucine-rich repeat	554..577	CDD:275380
		LRR_8	576..641	CDD:290566
		leucine-rich repeat	578..604	CDD:275380
		leucine-rich repeat	607..630	CDD:275380
		leucine-rich repeat	631..652	CDD:275380
		LRRCT	665..712	CDD:214507
		IG	734..823	CDD:214652
		Ig	735..823	CDD:143165
		I-set	834..924	CDD:254352	25/111 (23%)
		Ig	851..924	CDD:299845	23/92 (25%)
		IG	936..1027	CDD:214652	24/100 (24%)
		Ig	961..1020	CDD:143165	17/65 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910