Protein Alignment PAX7 and repo

DIOPT Version :10

• Sequence 1: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 145/550 - (26%)
• Similarity: 200/550 - (36%)
• Gaps: 161/550 - (29%)

Human    14 PAPGQNYPRTGFPL-EVSTPLGQGRVNQLGGVF----INGR------PL----PNHIRHKIVEMA 63
            |.|..|    |..| :.|:...|.:..||.|:.    :||:      |.    |..::|......
  Fly   133 PPPSHN----GILLHKQSSQQQQQQQQQLVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSP 193

Human    64 HHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGM 128
            ||         ...:.||  |..|.:......|..|:.||    ::..||
  Fly   194 HH---------LDHLDHG--SDGLLQDSSPVMINGGSAGG----KLKKPD--------------- 228

Human   129 FSWEIRDRLLKDG-----HCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSI 188
               |:..:|...|     ....|||.:|..:.....                   :....|...|
  Fly   229 ---EMCSQLEAGGAGVTPPSSSSTVVNGTTNGTGNA-------------------NSSSSAGVGI 271

Human   189 DGILGDKGN-----RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 248
            .|..|..|.     ...:||..:.:.| |...|::::||||||.||||||:||||..|||::.||
  Fly   272 QGAAGTAGGVAAPAAKKDGSSSKKKGD-PNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFARE 335

Human   249 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQL--PDSTYP 311
            |||.:..|:|:||||||.||||:|||.....:..    .:....|||.  ||.|..|  |.::||
  Fly   336 ELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTG----YIKTSTPPTA--TLNPGTLAPPFTSYP 394

Human   312 -TTTI----SQDGGSTVHRPQPLPPSTMHQGGLAAAAAA--ADTSSAYGA----------RH-SF 358
             |||:    |.|..::...|..|.|    |..|.:.||:  ...|..|||          || .:
  Fly   395 QTTTVTPPGSMDSWTSYQTPYELTP----QFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEY 455

Human   359 SSYSDSFMNPAAPS---NHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHG--------- 411
            .|.:...|.....|   |....|:||.|.|...:    .....|..||.::..:|.
  Fly   456 GSPTRMEMGATTGSVAGNGDESVANGGSYQTAEL----QTAQQQQLADGTLVTVHAHQQQQQQQQ 516

Human   412 -------GLDSATSISASCSQRADSIK--PGDSLPTSQAYCPPTYSTT---------GYSVD--- 455
                   ..:.|..:...|.|....::  ||.|....:|. ...|.||         |.|.|
  Fly   517 QLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQ-GQHYVTTATGGAASAGGTSSDDND 580

Human   456 -----------PVAGYQYGQYGQSECLVPW 474
                       .|:..|..|.|||..|.|:
  Fly   581 SGGMQTVIKSEEVSQQQQQQQGQSYVLPPF 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX7	NP_002575.1	paired box domain	34..164		28/148 (19%)
		PAX	34..163	CDD:238076	28/147 (19%)
		octapeptide	86..93		1/6 (17%)
		paired homeodomain	217..275		38/57 (67%)
		Homeodomain	218..274	CDD:459649	37/55 (67%)
		Pax7	347..385	CDD:403540	14/51 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		3/19 (16%)
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	32/47 (68%)