Protein Alignment PAX7 and sv

DIOPT Version :9

• Sequence 1: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 174/662 - (26%)
• Similarity: 239/662 - (36%)
• Gaps: 283/662 - (42%)

Human    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98
            |.|.||||||||:||||||:.:|.:|||:||:|:|||.||||||||||||||||.||.||||.:.
  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKA 239

Human    99 GAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIK 163
            |.||||||: ||||.|...|..||||||.||:||||||||.:..|.:..|||  ||||:|::|.|
  Fly   240 GVIGGSKPK-VATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPS--VSSINRIVRNK 301

Human   164 FGKKEE----------------------------------------------------------- 169
            ..:|.:
  Fly   302 AAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHAS 366

Human   170 -------------------EDEADKKEDDGEKKAK-HSIDGILG----------DKGNRLDEGSD 204
                               .:|........|::.. :||:||||          :..:.::..::
  Fly   367 IPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNN 431

Human   205 VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLT-----EARVQVW 264
            .||.    .|||:               .:|.:..|..:|::..:..:|.:::     :....:|
  Fly   432 TESS----CKRKR---------------IEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIW 477

Human   265 FSNRRARWRKQAGANQLAAFNHLL--PGGFPPT------GMPTLP------------PYQLPDST 309
                ..:|..:.....||...:|.  .|..|.|      |..|.|            ...|.||
  Fly   478 ----SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDS- 537

Human   310 YPTTTISQDGGSTVHRP-----------QPLPPSTMHQGGLAAAAAAADT--------------- 348
              .|||||. .|:::.|           .||.|.:||:..|:|.:....|
  Fly   538 --ITTISQT-QSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYT 599

Human   349 --------SSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVM------------------ 387
                    ||..|..|       ..|..::.||.:.|:|..:.|.:.
  Fly   600 SMTSLENCSSLVGQEH-------IVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCS 657

Human   388 ------------------------------SILGN----------PSA-VPPQPQADFS---ISP 408
                                          .:.||          ||: :|.||....|   |:|
  Fly   658 EDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINP 722

Human   409 LHG------------GLDSATSI-------SASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSV 454
            ...            ||.|..::       ||.||    |:.||.....:.||       |.|
  Fly   723 SENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCS----SVVPGSDYAYNPAY-------TQY-- 774

Human   455 DPVAGYQYGQYG 466
                |..||.||
  Fly   775 ----GGAYGSYG 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX7	NP_002575.1	paired box domain	34..164		87/129 (67%)
		PAX	34..163	CDD:238076	87/128 (68%)
		octapeptide	86..93		4/6 (67%)
		paired homeodomain	217..275		6/62 (10%)
		Homeobox	220..273	CDD:278475	5/57 (9%)
		Pax7	347..385	CDD:289156	10/60 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		9/33 (27%)
sv	NP_524633.3	PAX	175..299	CDD:128645	86/126 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810