Protein Alignment PAX7 and Poxm

DIOPT Version :9

• Sequence 1: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 144/389 - (37%)
• Similarity: 177/389 - (45%)
• Gaps: 85/389 - (21%)

Human    36 GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGA 100
            |.||||||||:|||||||..|.:|||:|..|||||.||||||||||||||||.||.|||||.|||
  Fly    11 GEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGA 75

Human   101 IGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFG 165
            ||||||| |.||.|...|.|.|:.:||:|:||||||||.:|.||::.|||  ||||||:||.|.|
  Fly    76 IGGSKPR-VTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPS--VSSISRILRNKLG 137

Human   166 KKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLE 230
            ....:               |:...::|...:  ..|..|.|...      |....:......|.
  Fly   138 SLGHQ---------------HTPGTVMGSGSS--SGGGSVSSNGG------QNNGTSASNNINLS 179

Human   231 ELEKAFERTHYPDIYTREELAQRTKL-----TEARVQVWFSNRRARWRKQAGANQLAAFNHLLPG 290
            .|.......|:|..:...:.|.....     ..|.......|  :.::..:.|   ||::...|.
  Fly   180 NLGNPGGGPHHPHHHHHHQSAAAAASAHHVHAHAHAHAHLYN--SIYQPYSAA---AAYSMKTPC 239

Human   291 GFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQ-GGLAAAAAAADTSSAYGA 354
            |.|.      ||              |..|.....|.|      || ..:|||||||...|::
  Fly   240 GSPS------PP--------------QGAGGQGSVPHP------HQLRSVAAAAAAAHWPSSH-- 276

Human   355 RHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQV------MSILGNPSAVPPQPQADFSISPLHGG 412
                 |.||...       |...|:...|.||      |..:|  |.|.|.|.....::...||
  Fly   277 -----SVSDILA-------HHQAVALRASCQVGVGVGGMGGMG--STVSPLPMTPSPVAGTAGG 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX7	NP_002575.1	paired box domain	34..164		91/127 (72%)
		PAX	34..163	CDD:238076	91/126 (72%)
		octapeptide	86..93		4/6 (67%)
		paired homeodomain	217..275		8/62 (13%)
		Homeobox	220..273	CDD:278475	7/57 (12%)
		Pax7	347..385	CDD:289156	7/37 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		5/19 (26%)
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	89/124 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910