Protein Alignment AK3 and Cmpk

DIOPT Version :10

• Sequence 1: NP_057366.2
• Gene: AK3 / 50808
• HGNCID: 17376
• Length: 227
• Species: Homo sapiens
• Sequence 2: NP_651456.1
• Gene: Cmpk / 43165
• FlyBaseID: FBgn0028833
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 55/207 - (26%)
• Similarity: 98/207 - (47%)
• Gaps: 39/207 - (18%)

Human    12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLR-GTEIGVLAKAFIDQGKLIPDDVMTRLA 75
            ::|.||:||||..|||...|:..|||:|||||:...| |:|.|.|.:.:|..||::|.:|...|.
  Fly    68 VLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYIRNGKIVPVEVTCSLL 132

Human    76 LHELKNLTQYSWLLDGFPRTLPQAEALDR--AYQID--TVINLNVPFEVIKQRLTARWIHPASGR 136
            .:.:|...:..:|:|||||.....:..:|  :.::|  .|:..:...:|..:|...|
  Fly   133 ENAMKASGKSRFLIDGFPRNQDNLDGWNRQMSEKVDFQFVLFFDCGEDVCVKRCLGR-------- 189

Human   137 VYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT-- 199
                              |:....|.||..:::.||:..|.:.:.|::::::..|.::....:
  Fly   190 ------------------GQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPD 236

Human   200 ------ETNKIW 205
                  |..||:
  Fly   237 AEEVFGEVEKIF 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AK3	NP_057366.2	ADK	12..190	CDD:395329	51/182 (28%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	37..66		14/29 (48%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	127..164		3/36 (8%)
Cmpk	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	55/207 (27%)