Protein Alignment AK3 and Ak1

DIOPT Version :10

• Sequence 1: NP_057366.2
• Gene: AK3 / 50808
• HGNCID: 17376
• Length: 227
• Species: Homo sapiens
• Sequence 2: NP_729792.1
• Gene: Ak1 / 39396
• FlyBaseID: FBgn0022709
• Length: 229
• Species: Drosophila melanogaster
• Alignment Length: 217
• Identity: 56/217 - (25%)
• Similarity: 97/217 - (44%)
• Gaps: 31/217 - (14%)

Human    12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRL-- 74
            |:|.||.||||..::|...:...|||||||||:.:..|::.|...:|.:..|.|:.:|.:..|
  Fly    37 ILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVMASGGLVSNDEVLSLLN 101

Human    75 -ALHELKNLTQYSWLLDGFPRTLPQA-EALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRV 137
             |:...|..:: .:|:||:||...|. |...|....|..:......:.:.||:.||
  Fly   102 DAITRAKGSSK-GFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMAR--------- 156

Human   138 YNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETN 202
                            .....::|:||..:|:..||..::..|..:||.|:.| .|...:..:.:
  Fly   157 ----------------AAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPK-TLTINAERDVD 204

Human   203 KIWPYVYAFLQTKVPQRSQKAS 224
            .|:..|...:...:.::.|.|:
  Fly   205 DIFLEVVQAIDCVLKKKQQNAA 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AK3	NP_057366.2	ADK	12..190	CDD:395329	50/181 (28%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	37..66		11/28 (39%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	127..164		3/36 (8%)
Ak1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	54/206 (26%)