Protein Alignment PAX6 and Poxm

DIOPT Version :9

• Sequence 1: NP_001355839.1
• Gene: PAX6 / 5080
• HGNCID: 8620
• Length: 503
• Species: Homo sapiens
• Sequence 2: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 412
• Identity: 142/412 - (34%)
• Similarity: 182/412 - (44%)
• Gaps: 110/412 - (26%)

Human    89 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 153
            |||||||||||||||::||.:|||||..|.|||||||.|:||:|||||||.||:|||||.|.|||
  Fly    13 VNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIG 77

Human   154 GSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQM 218
            ||||||.||:||:.|.:.|:..|.||||||||||||||:|...|:||||||:|:|||
  Fly    78 GSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRN-------- 134

Human   219 GADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQM 283
                   ||    |..|...|     |||.:       |.....|||    |:||||.
  Fly   135 -------KL----GSLGHQHT-----PGTVM-------GSGSSSGGG----SVSSNGG------- 165

Human   284 RLQLKRKLQRNRTSFTQE-QIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWR 347
                    |.|.||.:.. .:..|.......|:|......:.||
  Fly   166 --------QNNGTSASNNINLSNLGNPGGGPHHPHHHHHHQSAA--------------------- 201

Human   348 REEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPP 412
                       |:.:..|:...:.....:|..|.||.:..::::..:..|          |..||
  Fly   202 -----------AAASAHHVHAHAHAHAHLYNSIYQPYSAAAAYSMKTPCG----------SPSPP 245

Human   413 MPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHM--------QTHMNSQPMGT 469
            ..:....:     .|.|.|..|.:.....:...:..|.......|.        |..:....||.
  Fly   246 QGAGGQGS-----VPHPHQLRSVAAAAAAAHWPSSHSVSDILAHHQAVALRASCQVGVGVGGMGG 305

Human   470 SGTTSTGLISPGVSVPVQVPGS 491
            .|:|    :||....|..|.|:
  Fly   306 MGST----VSPLPMTPSPVAGT 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX6	NP_001355839.1	PAX	85..209	CDD:128645	87/119 (73%)
		Homeobox	295..348	CDD:395001	7/53 (13%)
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	87/119 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910