Protein Alignment PAX3 and CG11085

DIOPT Version :10

• Sequence 1: NP_852124.1
• Gene: PAX3 / 5077
• HGNCID: 8617
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 52/209 - (24%)
• Similarity: 76/209 - (36%)
• Gaps: 67/209 - (32%)

Human   190 GILSERASAPQSDEGSDIDSEP-------------DLPLK---RKQRRSRTTFTAEQLEELERAF 238
            |:|:..||....|..::..|.|             .|.|.   ||.||.||.||..||..|||.|
  Fly   115 GLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKF 179

Human   239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
            ....|..:..|.::|:...|:|.:|:.|:.|||.:|::|   |||
  Fly   180 RCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQ---NQL-------------------- 221

Human   304 TYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGF-SSYT 367
              :|.:..:|.|.....|                      :.....:....|.||   |. ||::
  Fly   222 --RLEQLRHQATMEKDFV----------------------VQDGGGAGGLGCCPS---GLSSSFS 259

Human   368 DSFVPPSGPSNPMN 381
            .:....:..|||.|
  Fly   260 AAAAAAAAASNPCN 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX3	NP_852124.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PAX	34..159	CDD:128645
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	37..93
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	113..161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..228		16/53 (30%)
		Homeodomain	220..276	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351		3/41 (7%)
		Pax7	347..391	CDD:403540	10/36 (28%)
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	23/55 (42%)