Protein Alignment PAX3 and CG11294

DIOPT Version :10

• Sequence 1: NP_852124.1
• Gene: PAX3 / 5077
• HGNCID: 8617
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_572500.1
• Gene: CG11294 / 31807
• FlyBaseID: FBgn0030058
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 196
• Identity: 70/196 - (35%)
• Similarity: 91/196 - (46%)
• Gaps: 43/196 - (21%)

Human   216 KRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
            :|:|||:|||||.:||:|||..|::|||||::.|||:|.|..|:||||||||.||||:|||||..
  Fly    21 RRRQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRISLSEARVQVWFQNRRAKWRKQARL 85

Human   281 NQLM-AFN-HLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQST 343
            ..|. |:. ..:..|.||.               ......|..|...:|..     |||...::.
  Fly    86 QLLQDAWRMRCLSLGTPPV---------------MGGGAVQGGSGNGATAR-----PPSQTPENL 130

Human   344 IPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQT 408
            ..::.||.    |....:|         |.||....|:|........|      .|.|  ||..|
  Fly   131 SSASKDSE----LAEVGNG---------PNSGSFTMMHPAFQQQHQQQ------QHQG--HQQAT 174

Human   409 D 409
            |
  Fly   175 D 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAX3	NP_852124.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PAX	34..159	CDD:128645
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	37..93
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	113..161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..228		8/11 (73%)
		Homeodomain	220..276	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351		7/41 (17%)
		Pax7	347..391	CDD:403540	9/43 (21%)
CG11294	NP_572500.1	Homeodomain	29..81	CDD:459649	34/51 (67%)