Protein Alignment PARN and parn

DIOPT Version :10

• Sequence 1: NP_002573.1
• Gene: PARN / 5073
• HGNCID: 8609
• Length: 639
• Species: Homo sapiens
• Sequence 2: NP_001307333.1
• Gene: parn / 791461
• ZFINID: ZDB-GENE-040426-880
• Length: 660
• Species: Danio rerio
• Alignment Length: 674
• Identity: 429/674 - (63%)
• Similarity: 511/674 - (75%)
• Gaps: 49/674 - (7%)

Human     1 MEIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALTNGFDTPEERYQKLKKHSMDFL 65
            ||:.|.|||..|.:|..|::||||.:|||||:||||||||||||||.|||||||.||:||||:||
Zfish     1 MEVTRQNFKEILPEVCNAVQEADFISIDGEFTGISDGPSVSALTNGLDTPEERYTKLRKHSMNFL 65

Human    66 LFQFGLCTFKYDYTDSKYITKSFNFYVFPKPFNRSSPDVKFVCQSSSIDFLASQGFDFNKVFRNG 130
            |||||:|||:||...|.||||:||||:|||||:|:|||:||:|||||||||||||||||||||:|
Zfish    66 LFQFGVCTFRYDQNQSTYITKAFNFYIFPKPFSRTSPDIKFICQSSSIDFLASQGFDFNKVFRSG 130

Human   131 IPYLNQEEERQLREQYDEKRSQANGAGALSYVSPN-TSKCPVTIPEDQKKFIDQVVEKIEDLLQS 194
            ||||.||||.||||||:|:|.|.||||.:||..|: |..|  .:||||::||..|.||:|.||::
Zfish   131 IPYLTQEEECQLREQYEERRGQMNGAGPVSYTPPSGTGVC--NVPEDQREFIRSVEEKVEALLKN 193

Human   195 EENKNLDLEPCTGFQRKLIYQTLSWKYPKGIHVETLETEKKERYIVISKVDEEERKRREQQKHAK 259
            .: :.||||||||||||||||||:.||.||:||||||||||||:|.|||||:|||:||||||..:
Zfish   194 TD-QTLDLEPCTGFQRKLIYQTLNSKYSKGLHVETLETEKKERFIQISKVDDEERRRREQQKQQR 257

Human   260 EQEELNDAVGFSRVIHAIANSGKLVIGHNMLLDVMHTVHQFYCPLPADLSEFKEMTTCVFPRLLD 324
            |||||||||||||||.||:.|||||:|||||||||||:|||..|||.:|.:|||:...|||||||
Zfish   258 EQEELNDAVGFSRVIRAISKSGKLVVGHNMLLDVMHTIHQFCGPLPEELDDFKEVAMTVFPRLLD 322

Human   325 TKLMASTQPFKDIINNTSLAELEKRLKETPFNPPKVESAEGFPSYDTASEQLHEAGYDAYITGLC 389
            |||||||||||:||:|||||||.|:|::.||.||..|..||..||||::||||||||||:|||||
Zfish   323 TKLMASTQPFKEIIHNTSLAELHKQLRQKPFRPPTTECPEGLQSYDTSTEQLHEAGYDAFITGLC 387

Human   390 FISMANYLGSFLSPPKIHVSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDLQPKRDHVLHVTFPK 454
            ||||||||||||:|||.|:||||||:|||:||||||||:||||||:.||||||||||||:|||||
Zfish   388 FISMANYLGSFLTPPKSHISARSKLLEPFYNKLFLMRVIDIPYLNMSGPDLQPKRDHVLYVTFPK 452

Human   455 EWKTSDLYQLFSAFGNIQISWIDDTSAFVSLSQPEQVKIAVNTSKYAESYRIQTYAEYMGRKQEE 519
            ||||||||||||||||||:||:|||||||||||.|||:||:|||:|||||||||||||:..:|:.
Zfish   453 EWKTSDLYQLFSAFGNIQVSWVDDTSAFVSLSQTEQVQIAMNTSRYAESYRIQTYAEYLQSRQKN 517

Human   520 KQIKRKWTEDSWKEADSKRLNPQCIPYTLQNHYYRNNSFTAPSTVGKRNLSPSQEEA--GLEDG- 581
            ....|||..|.|  ||:.  .|.....|...:.:.:|...|.    ||::|||.:|.  |.:..
Zfish   518 THSSRKWASDGW--ADTS--YPSVAMTTASGYSHTDNRHQAV----KRSISPSLDEQNHGADSSW 574

Human   582 ---------VSGEISDTELEQTDSCAEP----------------------LSEGRKKAKKLKRMK 615
                     ..|..:.|..:...||..|                      .|..:.:.|:.::.|
Zfish   575 TNYSVKKIKTEGSCTQTYADVAGSCDWPRLQADEGGASVSPVAEEAELDEFSANQSQGKRSRKHK 639

Human   616 KELSPAGSISKNSPATLFEVPDTW 639
            |..|.|   |:.:|..||:||..|
Zfish   640 KRKSDA---SETTPPALFDVPQVW 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARN	NP_002573.1	CAF1	5..390	CDD:461457	281/385 (73%)
		RNA_bind	438..512	CDD:400835	66/73 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	560..639		25/112 (22%)
parn	NP_001307333.1	CAF1	3..388	CDD:461457	281/387 (73%)
		RNA_bind	436..510	CDD:400835	66/73 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	606..660		12/56 (21%)