Protein Alignment PARN and parn

DIOPT Version :10

• Sequence 1: NP_002573.1
• Gene: PARN / 5073
• HGNCID: 8609
• Length: 639
• Species: Homo sapiens
• Sequence 2: NP_001184102.1
• Gene: parn / 733861
• XenbaseID: XB-GENE-1003103
• Length: 632
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 477/639 - (74%)
• Similarity: 546/639 - (85%)
• Gaps: 7/639 - (1%)

Human     1 MEIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALTNGFDTPEERYQKLKKHSMDFL 65
            ||:.|||||.||.|||:|||||||.||||||||||||||||.||||||||||||.|||||||:||
 Frog     1 MEMTRSNFKDNLPKVYKAIEEADFLAIDGEFSGISDGPSVSTLTNGFDTPEERYTKLKKHSMEFL 65

Human    66 LFQFGLCTFKYDYTDSKYITKSFNFYVFPKPFNRSSPDVKFVCQSSSIDFLASQGFDFNKVFRNG 130
            |||||||||.||.|::||..||||||:|||||||:|||.|||||||||||||:||||||||||||
 Frog    66 LFQFGLCTFNYDNTEAKYFMKSFNFYIFPKPFNRNSPDKKFVCQSSSIDFLANQGFDFNKVFRNG 130

Human   131 IPYLNQEEERQLREQYDEKRSQANGAGALSYVSPNTSKCPVTIPEDQKKFIDQVVEKIEDLLQSE 195
            |||||||||:|||:||:|:|||:|||.|:||||||.||.||:||::||.|||:|||::||.|::|
 Frog   131 IPYLNQEEEKQLRDQYEERRSQSNGASAMSYVSPNASKTPVSIPDEQKGFIDKVVERVEDFLKNE 195

Human   196 ENKNLDLEPCTGFQRKLIYQTLSWKYPKGIHVETLETEKKERYIVISKVDEEERKRREQQKHAKE 260
            : |::|||||||:|||||||||:||||:||||||||:|||||||||||||||||||.||||.|||
 Frog   196 Q-KSMDLEPCTGYQRKLIYQTLNWKYPRGIHVETLESEKKERYIVISKVDEEERKRMEQQKQAKE 259

Human   261 QEELNDAVGFSRVIHAIANSGKLVIGHNMLLDVMHTVHQFYCPLPADLSEFKEMTTCVFPRLLDT 325
            :|||:|||||||:|.||::|||||:|||||||:|||:|||:|.||.:|:||||:|.|||||:|||
 Frog   260 REELDDAVGFSRIIQAISSSGKLVVGHNMLLDIMHTIHQFFCQLPDELNEFKEVTNCVFPRVLDT 324

Human   326 KLMASTQPFKDIINNTSLAELEKRLKETPFNPPKVESAEGFPSYDTASEQLHEAGYDAYITGLCF 390
            ||||||.|||:||.|||||||||||||.||.||||:||||||||:||||||||||||||||||||
 Frog   325 KLMASTNPFKEIIYNTSLAELEKRLKEAPFKPPKVDSAEGFPSYNTASEQLHEAGYDAYITGLCF 389

Human   391 ISMANYLGSFLSPPKIHVSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDLQPKRDHVLHVTFPKE 455
            |||||||||||||||.:||:|||:|.||||||||||:||||||||||||||||||:||||.||||
 Frog   390 ISMANYLGSFLSPPKGYVSSRSKIIRPFFNKLFLMRIMDIPYLNLEGPDLQPKRDNVLHVAFPKE 454

Human   456 WKTSDLYQLFSAFGNIQISWIDDTSAFVSLSQPEQVKIAVNTSKYAESYRIQTYAEYMGRKQEEK 520
            |||||||||||||||||:|||||||||||||.|:||:||||||||||||||||||||:.:|.||.
 Frog   455 WKTSDLYQLFSAFGNIQVSWIDDTSAFVSLSHPDQVQIAVNTSKYAESYRIQTYAEYVEKKNEEN 519

Human   521 QIKRKWTEDSWKEADSKRLNPQCIPYTLQNHYYRNNSFTAPSTVGKRNLSPSQEEAGLEDGVSGE 585
            |.||||.||.||:.:.|||..|...|..|...:..|.|.|||...||::||.|||...|:
 Frog   520 QTKRKWAEDGWKDLERKRLKTQYNSYIPQTPVFYGNCFVAPSYAVKRSMSPIQEETASEN----- 579

Human   586 ISDTELEQTDSCAEPLSEGRKKAKKLKRMKKELSPAGSISKNSPATLFEVPDTW 639
            ..:...::.|......:|..||.|..||.|.:.:|. ..|.:..:.||||||||
 Frog   580 TEEVRAQEDDPSNPGATEQGKKPKNHKRQKTDSTPP-ETSDSGSSVLFEVPDTW 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARN	NP_002573.1	CAF1	5..390	CDD:461457	314/384 (82%)
		RNA_bind	438..512	CDD:400835	67/73 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	560..639		27/78 (35%)
parn	NP_001184102.1	CAF1	4..389	CDD:461457	314/385 (82%)
		RNA_bind	437..511	CDD:400835	67/73 (92%)