| Sequence 1: | NP_002568.2 | Gene: | PAK2 / 5062 | HGNCID: | 8591 | Length: | 524 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_011856.1 | Gene: | STE20 / 856382 | SGDID: | S000000999 | Length: | 939 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 689 | Identity: | 270/689 - (39%) |
|---|---|---|---|
| Similarity: | 346/689 - (50%) | Gaps: | 185/689 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 11 PPAPPVRMSSTIFSTGGKDPLSANHSL----------KPLPSVPEEKKPRHKIISIFSG------ 59
Human 60 -------TEK----GSKKKEKERP----------------------------------------- 72
Human 73 ---EISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY---- 130
Human 131 DSNTVKQKYLSF-------------TPPEK--DGFP------------SGTPALNAKGTEAPAVV 168
Human 169 TEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPV------------------------------- 202
Human 203 ------------PAP---------VGDSHV----------------------DGAAKSLDKQKKK 224
Human 225 TKMTDEE-----IMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK 284
Human 285 QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVC 349
Human 350 RECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 414
Human 415 VTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNR 479
Human 480 CLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLIMAAK 517 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PAK2 | NP_002568.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..81 | 27/140 (19%) | |
| Autoregulatory region. /evidence=ECO:0000250 | 69..137 | 33/115 (29%) | |||
| GTPase-binding. /evidence=ECO:0000250 | 69..112 | 20/86 (23%) | |||
| PBD | 73..130 | CDD:307091 | 29/56 (52%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 143..164 | 9/34 (26%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 169..188 | 4/18 (22%) | |||
| STKc_PAK2 | 229..524 | CDD:132986 | 187/295 (63%) | ||
| Nuclear localization signal | 245..251 | 3/5 (60%) | |||
| STE20 | NP_011856.1 | PBD | 336..394 | CDD:395634 | 30/57 (53%) |
| STKc_PAK | 619..872 | CDD:270789 | 172/252 (68%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 359 | 1.000 | Domainoid score | I151 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0578 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 448 | 1.000 | Inparanoid score | I296 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000763 | |
| OrthoInspector | 1 | 1.000 | - | - | otm52977 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100484 | |
| Panther | 1 | 1.100 | - | - | O | PTHR48015 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1405 |
| SonicParanoid | 1 | 1.000 | - | - | X799 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.890 | |||||