Protein Alignment UBQLN3 and Ubqln3

DIOPT Version :10

• Sequence 1: NP_059509.1
• Gene: UBQLN3 / 50613
• HGNCID: 12510
• Length: 655
• Species: Homo sapiens
• Sequence 2: NP_001371113.1
• Gene: Ubqln3 / 244178
• MGIID: 3045291
• Length: 681
• Species: Mus musculus
• Alignment Length: 658
• Identity: 485/658 - (73%)
• Similarity: 533/658 - (81%)
• Gaps: 3/658 - (0%)

Human     1 MAKGGEALPQGSPAPVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLVLIF 65
            |||.||||||||.||.||..||:||||||||||||||.|||||:||||:||.||||||:||||||
Mouse    24 MAKSGEALPQGSLAPAQDSQLIRVTVKTPKDKEDFSVVDTCTIRQLKEKISHRFKAHPNQLVLIF 88

Human    66 AGKILKDPDSLAQCGVRDGLTVHLVIKRQHRAMGNECPAASVPTQGPSPGSLPQPSSIYPADGPP 130
            |||||||||||||||||||||||||||.|.|.:|.|||:..|...||:||.:||.||:|..||.|
Mouse    89 AGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTIGTECPSPPVSIPGPNPGEIPQSSSVYSVDGSP 153

Human   131 AFSLGLLTGLSRLGLAYRGFPDQPSSLMRQHVSVPEFVTQLIDDPFIPGLLSNTGLVRQLVLDNP 195
            :||||:|||||.|||....|.|||.|||.||:||||.|.||:|||||.|||||||||||||||||
Mouse   154 SFSLGVLTGLSGLGLTSGSFSDQPGSLMWQHISVPELVAQLVDDPFIQGLLSNTGLVRQLVLDNP 218

Human   196 HMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMIRSQDRVLSNLESIPGGYNVLCTMYTD 260
            |||.|||.|||||||||||||||||:||||||:|||||:|||||.||||||||||||||.|||||
Mouse   219 HMQHLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTD 283

Human   261 IMDPMLNAVQEQFGGNPFATATTDNATTTTSQPSRMENCDPLPNPWTSTHGGSGSRQ---GRQDG 322
            ||||||||||||||||||.||||.:.|||:|||||.|||||||||||||:|.||.||   |||.|
Mouse   284 IMDPMLNAVQEQFGGNPFVTATTASTTTTSSQPSRTENCDPLPNPWTSTYGVSGGRQGRGGRQSG 348

Human   323 DQDAPDIRNRFPNFLGIIRLYDYLQQLHENPQSLGTYLQGTASALSQSQEPPPSVNRVPPSSPSS 387
            ||||.:.|||.|:|||.|.|:||||||||..|||.:|||||....:.|||.|.|.|||||:.|||
Mouse   349 DQDASENRNRLPSFLGNIGLFDYLQQLHETSQSLESYLQGTVPTSNPSQESPLSGNRVPPTLPSS 413

Human   388 QEPGSGQPLPEESVAIKGRSSCPAFLRYPTENSTGQGGDQDGAGKSSTGHSTNLPDLVSGLGDSA 452
            .:.||||.||:|||||||:||||||||:.|||||||||....|||.|||.||:||:|.|.:||||
Mouse   414 PKSGSGQSLPKESVAIKGKSSCPAFLRHSTENSTGQGGSLHDAGKGSTGPSTSLPNLTSQIGDSA 478

Human   453 NRVPFAPLSFSPTAAIPGIPEPPWLPSPAYPRSLRPDGMNPAPQLQDEIQPQLPLLMHLQAAMAN 517
            ||..|.....|..:|.||:||.||||...|.||||..|.|..|::|:||..|||||:|||.||||
Mouse   479 NRSSFVSTPSSLMSATPGVPESPWLPPTGYSRSLRSAGTNQVPRIQNEIHQQLPLLLHLQTAMAN 543

Human   518 PRALQALRQIEQGLQVLATEAPRLLLWFMPCLAGTGSVAGGIESREDPLMSEDPLPNPPPEVFPA 582
            ||.:|||.|||||||:||||||||||||||||.|...|.||.|:||..:|||||.|.|.|::..|
Mouse   544 PRVMQALLQIEQGLQILATEAPRLLLWFMPCLTGLNGVTGGTEAREGVVMSEDPRPTPTPQISLA 608

Human   583 LDSAELGFLSPPFLHMLQDLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDA 647
            ..|.|||..|.|||.:||.|.||||||||.||||:|||||||:|||||.||||||||||.|||||
Mouse   609 QGSTELGIHSSPFLQVLQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDA 673

Human   648 AVEKLRQS 655
            ||||||:|
Mouse   674 AVEKLRKS 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN3	NP_059509.1	Ubl_PLICs	20..92	CDD:340506	64/71 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..124		11/21 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..330		40/55 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..399		19/34 (56%)
		PHA03378	<368..627	CDD:223065	169/258 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	412..447		23/34 (68%)
		UBA_PLICs	615..654	CDD:270582	34/38 (89%)
Ubqln3	NP_001371113.1	Ubl_PLICs	43..115	CDD:340506	64/71 (90%)
		STI1	212..256	CDD:128966	39/43 (91%)
		UBA_PLICs	641..678	CDD:270582	32/36 (89%)