Protein Alignment ATP5F1B and ATPsynbeta

DIOPT Version :9

• Sequence 1: NP_001677.2
• Gene: ATP5F1B / 506
• HGNCID: 830
• Length: 529
• Species: Homo sapiens
• Sequence 2: NP_001259081.1
• Gene: ATPsynbeta / 43829
• FlyBaseID: FBgn0010217
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 526
• Identity: 438/526 - (83%)
• Similarity: 467/526 - (88%)
• Gaps: 30/526 - (5%)

Human     1 MLGFVGRVAAAPASGALRRLTPSASLPPAQLLLRAAPTAVHPVRDYAAQTSPSPKAGAATGRIVA 65
            :|.|:|:::.||.|                            .|.:||:.:.:  |.||.|:|||
  Fly    14 LLPFLGQLSTAPFS----------------------------ARSHAAKAAKA--AAAANGKIVA 48

Human    66 VIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGA 130
            |||||||||||:.||||||||||..|..||||||||||||:|||||||||||||||||||||:|.
  Fly    49 VIGAVVDVQFDDNLPPILNALEVDNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDTGY 113

Human   131 PIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAP 195
            ||:||||.||||||:|||||||||||||.|.:.|.||||||||::||||||||||||||||||||
  Fly   114 PIRIPVGAETLGRIINVIGEPIDERGPIDTDKTAAIHAEAPEFVQMSVEQEILVTGIKVVDLLAP 178

Human   196 YAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKD 260
            ||||||||||||||||||||||||||||||||||||||||||||||||||||:||||.|||:|||
  Fly   179 YAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYNEMIEGGVISLKD 243

Human   261 ATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRI 325
            .||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   244 KTSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRI 308

Human   326 PSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIA 390
            |||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   309 PSAVGYQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIA 373

Human   391 ELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVS 455
            ||||||||||||||||||||||:|.|||:|||||||||||||||||||||||||||||||||||:
  Fly   374 ELGIYPAVDPLDSTSRIMDPNIIGQEHYNVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVA 438

Human   456 RARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKA 520
            ||||||||||||||||||||||.||||||::|||||..||||:||||||.||||||||||.|.||
  Fly   439 RARKIQRFLSQPFQVAEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVAFYMVGPIEEVVEKA 503

Human   521 DKLAEE 526
            |:||:|
  Fly   504 DRLAKE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP5F1B	NP_001677.2	PRK09280	58..524	CDD:236447	425/465 (91%)
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	423/462 (92%)
		ATP-synt_ab_N	46..112	CDD:280947	58/65 (89%)
		F1-ATPase_beta	114..393	CDD:238553	263/278 (95%)
		ATP-synt_ab_C	401..508	CDD:278722	94/106 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156632
Domainoid	1	1.000	420	1.000	Domainoid score	I634
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1273
Inparanoid	1	1.050	837	1.000	Inparanoid score	I453
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62497
OrthoDB	1	1.010	-	-		D278669at33208
OrthoFinder	1	1.000	-	-		FOG0001822
OrthoInspector	1	1.000	-	-		oto88383
orthoMCL	1	0.900	-	-		OOG6_100608
Panther	1	1.100	-	-	LDO	PTHR15184
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770