| Sequence 1: | NP_001122092.1 | Gene: | PAK1 / 5058 | HGNCID: | 8590 | Length: | 553 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_011856.1 | Gene: | STE20 / 856382 | SGDID: | S000000999 | Length: | 939 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 631 | Identity: | 267/631 - (42%) |
|---|---|---|---|
| Similarity: | 344/631 - (54%) | Gaps: | 141/631 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Human 2 SNNGLDIQDKPPAPPMRNT-STMIGAGSK------DAGTLNHGSKPLPPNPEEKKKKDRFYRSIL 59
Human 60 PGDKTNKKKEKERP---------------EISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQT 109
Human 110 SNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNAL-NVKAVSETPA---- 169
Human 170 -VPPVSEDE--------------------DDDDDDATP---PPVIAPRPEHTKSVYTRSVIEPL- 209
Human 210 --------------PVTPTR-----------------DVATSPISPTENNTTP------------ 231
Human 232 --PDALTRNT-------------------EKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEK 275
Human 276 IGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL 340
Human 341 WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 405
Human 406 TDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPL 470
Human 471 RALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELL 516 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PAK1 | NP_001122092.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..77 | 20/96 (21%) | |
| Autoregulatory region | 70..140 | 32/84 (38%) | |||
| PBD | 74..128 | CDD:334253 | 28/53 (53%) | ||
| GTPase-binding | 75..105 | 16/29 (55%) | |||
| Interaction with CRIPAK. /evidence=ECO:0000269|PubMed:16278681 | 132..270 | 42/231 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 159..198 | 14/67 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 211..251 | 14/89 (16%) | |||
| STKc_PAK_I | 262..517 | CDD:270814 | 180/255 (71%) | ||
| STE20 | NP_011856.1 | PBD | 336..394 | CDD:395634 | 29/57 (51%) |
| STKc_PAK | 619..872 | CDD:270789 | 176/248 (71%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 359 | 1.000 | Domainoid score | I151 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0578 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 1 | 1.000 | - | - | H1936 | |
| Inparanoid | 1 | 1.050 | 448 | 1.000 | Inparanoid score | I296 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S857 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000763 | |
| OrthoInspector | 1 | 1.000 | - | - | otm52977 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100484 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48015 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1405 |
| SonicParanoid | 1 | 1.000 | - | - | X799 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.840 | |||||