Protein Alignment SERPINB2 and Spn42Dd

DIOPT Version :9

• Sequence 1: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 403
• Identity: 123/403 - (30%)
• Similarity: 208/403 - (51%)
• Gaps: 53/403 - (13%)

Human    15 LFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPENFTSC 79
            :::.|:|:...|||.:||.||.:.::||:||:.|||    ||.||                 ::.
  Fly    21 IYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGST----AKELQ-----------------SAL 64

Human    80 GFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRL 144
            |              |.::..:.:.:.:.:|.:.:.......:|:..|:::.....|..:.|...
  Fly    65 G--------------LPSEDKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLA 115

Human   145 CQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWK 209
            .::.:.||.:::. |.....|.::||.||..||.|||..::..||:..|.:.:||||:||||:|:
  Fly   116 VREPFKSEAESIS-LTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWE 179

Human   210 TPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIA 273
            :.|:........|:|.:.:..|||||.........|..||.||::||||. .::||.:.||.|:
  Fly   180 SKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREV- 243

Human   274 DVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRA 338
               .||..||.:|.      ..::..:|: ||.:.:|:||:|...||:..|..:|:.:.|. .::
  Fly   244 ---EGLSALEEKIV------GFARPLVAK-EVYLKLPKFKIEFRDELKETLEKLGIRELFT-DKS 297

Human   339 NFSGM-SERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKI 402
            :.||: ::::...:|:|.|:|.::|||||.|||..|...:|.|.|. ....:|||||.|:|  :.
  Fly   298 DLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGF-STFLMADHPFAFVI--RD 359

Human   403 TNCILFFGRFSSP 415
            .|.|.|.||..||
  Fly   360 ANTIYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	121/401 (30%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	120/398 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930