Protein Alignment SERPINE1 and Spn88Eb

DIOPT Version :10

• Sequence 1: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Sequence 2: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 375
• Identity: 97/375 - (25%)
• Similarity: 175/375 - (46%)
• Gaps: 36/375 - (9%)

Human    37 DFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA--MGFKIDDKGMAPALR 99
            ||.:.:.:|:.:.....|:.|||:...:.|.:...::..:|::::..|  :|:.::.:.:..:..
  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYT 104

Human   100 HLYKELMGPWNKD--EISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDF-SEVERARFIIND 161
            ...::....|.:.  |:|:.:.|||.|.:.:..    .|..|.....|::|| ::.|.....|||
  Fly   105 LAQRQDEFRWRQSPMELSSANRIFVDRTINVSN----KFNTLLYGATKELDFKNDPETGLKEIND 165

Human   162 WVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMA 226
            |:...|...|.::|....:...|.|||.||.|..|||.:.|....|..:.|..::.....|.||.
  Fly   166 WIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMH 230

Human   227 QTNKFNYTEFTTPDGHYYDILELPY---------HGDT------LSMFIAAPYEKEVPLSALTNI 276
            :|..|   :.|..:|....|::|||         |..|      :||.|..|...::.|:.:.:.
  Fly   231 KTGAF---KMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISR 292

Human   277 LSAQLISHWKGNMTRLPRL--LVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL-SDQEPL 338
            |:|..:..|...  .||:.  |.||||..|..::|...|..:|:..||.: .|.|..| :|...|
  Fly   293 LNADSVKKWFER--ALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTR-NATFGDLTADPISL 354

Human   339 HVAQALQKVKIEVNESGTVASSSTAVIV---SARMAPEEIIMDRPFLFVV 385
            .:..|....||:|:|.|:.|:::|.::|   |.:..|.:...:.||:|::
  Fly   355 VIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLI 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	97/375 (26%)
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	97/375 (26%)