DRSC/TRiP Functional Genomics Resources

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Protein Alignment PAH and PHA2

DIOPT Version :10

Sequence 1:NP_000268.1 Gene:PAH / 5053 HGNCID:8582 Length:452 Species:Homo sapiens
Sequence 2:NP_014083.2 Gene:PHA2 / 855400 SGDID:S000005260 Length:334 Species:Saccharomyces cerevisiae


Alignment Length:91 Identity:24/91 - (26%)
Similarity:40/91 - (43%) Gaps:22/91 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    42 KEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYE-------FFTHLDKRSLPALTNIIKILR 99
            :::.|:|..||.:.:.:.:|:..|.|||..|  ||::       |..:..:::.|  .|..|.  
Yeast   250 QDDPGSLVDVLNILKIHSLNMCSINSRPFHL--DEHDRNWRYLFFIEYYTEKNTP--KNKEKF-- 308

Human   100 HDIGATVHELSRDKKKDTVPW--FPR 123
                   :|...||.|....|  |||
Yeast   309 -------YEDISDKSKQWCLWGTFPR 327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PAHNP_000268.1 Phe4hydrox_tetr 20..452 CDD:130335 24/91 (26%)
PHA2NP_014083.2 PBP2_PDT_like 7..226 CDD:270250
ACT_CM-PDT 243..326 CDD:153177 21/88 (24%)
Blue background indicates that the domain is not in the aligned region.

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