Protein Alignment PAH and Pah

DIOPT Version :10

• Sequence 1: NP_000268.1
• Gene: PAH / 5053
• HGNCID: 8582
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_036751.2
• Gene: Pah / 24616
• RGDID: 3248
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 452
• Identity: 417/452 - (92%)
• Similarity: 435/452 - (96%)
• Gaps: 0/452 - (0%)

Human     1 MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHI 65
            |:..||||..|.||||||||||||||||.||||||||||||||||||||||||||||||:|||||
  Rat     1 MAAVVLENGVLSRKLSDFGQETSYIEDNSNQNGAISLIFSLKEEVGALAKVLRLFEENDINLTHI 65

Human    66 ESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDR 130
            |||||||.||||||||:|||||.|.|.:|||.||:|||||||||||||:|:||||||||||||||
  Rat    66 ESRPSRLNKDEYEFFTYLDKRSKPVLGSIIKSLRNDIGATVHELSRDKEKNTVPWFPRTIQELDR 130

Human   131 FANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLK 195
            |||||||||||||||||||||||||||||||||||||||||||||||||.||||:||||||:|||
  Rat   131 FANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEEKQTWGTVFRTLK 195

Human   196 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAF 260
            :|||||||||:|||||||||||||.||||||||||||||||||||||||||||||||||||||||
  Rat   196 ALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAF 260

Human   261 RVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIY 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 RVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIY 325

Human   326 WFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAE 390
            ||||||||||:|||||||||||||||||||||||:|||||||||||.|.|.|:||||||||||||
  Rat   326 WFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSDKPKLLPLELEKIACQEYSVTEFQPLYYVAE 390

Human   391 SFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
            ||:|||||||.|||||||||||||||||||:|||||||||||||||||||:||||:||||||
  Rat   391 SFSDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNTQQLKILADSINSEVGILCNALQKIK 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAH	NP_000268.1	Phe4hydrox_tetr	20..452	CDD:130335	402/431 (93%)
Pah	NP_036751.2	Phe4hydrox_tetr	20..452	CDD:130335	402/431 (93%)