Protein Alignment PAH and Pah

DIOPT Version :10

• Sequence 1: NP_000268.1
• Gene: PAH / 5053
• HGNCID: 8582
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_032803.2
• Gene: Pah / 18478
• MGIID: 97473
• Length: 453
• Species: Mus musculus
• Alignment Length: 452
• Identity: 418/452 - (92%)
• Similarity: 435/452 - (96%)
• Gaps: 0/452 - (0%)

Human     1 MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHI 65
            |:..||||..|.||||||||||||||||.|||||:|||||||||||||||||||||||::|||||
Mouse     1 MAAVVLENGVLSRKLSDFGQETSYIEDNSNQNGAVSLIFSLKEEVGALAKVLRLFEENEINLTHI 65

Human    66 ESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDR 130
            |||||||.||||||||:|||||.|.|.:|||.||:|||||||||||||:|:||||||||||||||
Mouse    66 ESRPSRLNKDEYEFFTYLDKRSKPVLGSIIKSLRNDIGATVHELSRDKEKNTVPWFPRTIQELDR 130

Human   131 FANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLK 195
            |||||||||||||||||||||||||||||||||||||||||||||||||.|||:|||||||:|||
Mouse   131 FANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEERKTWGTVFRTLK 195

Human   196 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAF 260
            :|||||||||:|||||||||||||.||||||||||||||||||||||||||||||||||||||||
Mouse   196 ALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAF 260

Human   261 RVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIY 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 RVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIY 325

Human   326 WFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAE 390
            ||||||||||:|||||||||||||||||||||||:|||||||||||||.|.||||||||||||||
Mouse   326 WFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSDKPKLLPLELEKTACQEYTVTEFQPLYYVAE 390

Human   391 SFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
            ||||||||||.|||||||||||||||||||:|||||||||||||||||||:||||.||||||
Mouse   391 SFNDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNTQQLKILADSINSEVGILCHALQKIK 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAH	NP_000268.1	Phe4hydrox_tetr	20..452	CDD:130335	403/431 (94%)
Pah	NP_032803.2	Phe4hydrox_tetr	20..452	CDD:130335	403/431 (94%)