| Sequence 1: | NP_001350640.1 | Gene: | DUOX2 / 50506 | HGNCID: | 13273 | Length: | 1548 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001189281.1 | Gene: | CG42331 / 42948 | FlyBaseID: | FBgn0259233 | Length: | 1615 | Species: | Drosophila melanogaster |
| Alignment Length: | 731 | Identity: | 181/731 - (24%) |
|---|---|---|---|
| Similarity: | 284/731 - (38%) | Gaps: | 159/731 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Human 3 RARPEALMLLGALLTGSLGPSGSQDALSLPWEVQRYDGWFNNLRHHERGAVGCRLQRRVPANYAD 67
Human 68 G---VYQALEEPQLPNPRRLS---NAATRGIAGLPSLHNRTVLGVFFGYHVLSDVVSV------- 119
Human 120 -ETPGC-------PAEFLNIRIPPGDPVF-------------DPDQRGDVVLPFQRSRWDPETGR 163
Human 164 SPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRDSQNPLLMWAAPDPA 228
Human 229 TGQNGPRGLYA-----FGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKR 288
Human 289 VIATYQNIAVYEWLPSFLQKTLPE-----------YTGYRPFLDPSISPEFVVASEQFFSTMVPP 342
Human 343 GVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRE---NPNLNSTQEVNELLLGMASQISELEDN 404
Human 405 IVVEDLRDY-WPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVL 468
Human 469 EATAALYNQDLSQLELLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGL---F 527
Human 528 SKKEIEDIRNTTLRDVLVAVINIDPSALQPNVFV------------------------WHKGAPC 568
Human 569 PQ---PKQLTTDGLPQCAPLTVLDFFEGSSPGFAITIIALCCLPLVSLLLSGVVAYFRGREHK-- 628
Human 629 ----KLQKKLKESVKK 640 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DUOX2 | NP_001350640.1 | Peroxidase-like, mediates peroxidase activity. /evidence=ECO:0000250 | 30..596 | 166/652 (25%) | |
| dual_peroxidase_like | 38..594 | CDD:188652 | 166/642 (26%) | ||
| EFh_PEF | <764..858 | CDD:330173 | |||
| EFh | 824..885 | CDD:238008 | |||
| EF-hand_7 | 857..929 | CDD:316058 | |||
| Interaction with TXNDC11. /evidence=ECO:0000250 | 960..1245 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 971..991 | ||||
| Ferric_reduct | 1088..1223 | CDD:307763 | |||
| NOX_Duox_like_FAD_NADP | 1274..1548 | CDD:99783 | |||
| CG42331 | NP_001189281.1 | An_peroxidase | 183..699 | CDD:281139 | 155/576 (27%) |
| peroxinectin_like | 328..696 | CDD:188655 | 115/403 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||