Protein Alignment RRM2B and RnrS

DIOPT Version :10

• Sequence 1: NP_001165948.1
• Gene: RRM2B / 50484
• HGNCID: 17296
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_525111.1
• Gene: RnrS / 36280
• FlyBaseID: FBgn0011704
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 255/349 - (73%)
• Similarity: 297/349 - (85%)
• Gaps: 3/349 - (0%)

Human    78 AKDDAWRPQAGRSSSDTNESEIKSNE---EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAE 139
            ||:.:.....|:|::...|..:...:   |||||::.||||||||||.|||:|||:|:|||||.|
  Fly    45 AKESSTVNGIGKSANSLMEKSVTPFDPSLEPLLRENPRRFVIFPIQYHDIWQMYKKAEASFWTVE 109

Human   140 EVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIEN 204
            ||||||||..|::||.||::||||:||||||||||||||||||||||||:.||||||||||.:||
  Fly   110 EVDLSKDLTDWHRLKDDERHFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMEN 174

Human   205 VHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 269
            |||||||:|||||||||.:||:|||||||||.||:||||||.||:.:.:.||||::|||||||:|
  Fly   175 VHSEMYSVLIDTYIRDPHQREYLFNAIETMPAVKRKADWALSWISSKSANFGERIIAFAAVEGIF 239

Human   270 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIE 334
            ||||||:|||||||||||||||||||||||||||||||.||||:||.:|..||:.|||.|||.||
  Fly   240 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFAVLMFQHLVQRPKRERIIEIIRDAVAIE 304

Human   335 QEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKR 399
            |||||:||||.||||||.||.|||||||||||||||..|::..:|||:|||.|||:||||||||:
  Fly   305 QEFLTDALPVNLIGMNCDLMSQYIEFVADRLLVELGVGKIYNTKNPFNFMEMISLDGKTNFFEKK 369

Human   400 VSEYQRFAVMAETTDNVFTLDADF 423
            |.||||..|::...||||||||||
  Fly   370 VGEYQRMGVVSNPLDNVFTLDADF 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RRM2B	NP_001165948.1	Ferritin_like	104..423	CDD:469698	248/318 (78%)
RnrS	NP_525111.1	Ferritin_like	74..393	CDD:469698	248/318 (78%)