Protein Alignment Muc26B and KRTAP10-4

DIOPT Version :10

• Sequence 1: NP_652552.1
• Gene: Muc26B / 50424
• FlyBaseID: FBgn0040950
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_941960.2
• Gene: KRTAP10-4 / 386672
• HGNCID: 20521
• Length: 401
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 91/427 - (21%)
• Similarity: 142/427 - (33%)
• Gaps: 130/427 - (30%)

  Fly    51 RALVPGSCSQYYECQSGVALVNVCSRFFDAKAQGCVNYNTGCIEFQPASASSPVGGSIAAVPCAE 115
            |..:||||..             ||..:  :...|           |.|...|        ||.
Human    13 RVCLPGSCDS-------------CSDSW--QVDDC-----------PESCCEP--------PCC- 42

  Fly   116 ETTTCAPQIITTTTCTPASVTTTTTCAPTTTTTCAPTTTTTCAPTTTTTCAPT--TTTTC----- 173
            ..:.|||....:..|||.| ..::.|.|   .||.|   :.|....|::|.|:  ..::|
Human    43 APSCCAPAPCLSLVCTPVS-RVSSPCCP---VTCEP---SPCQSGCTSSCTPSCCQQSSCQLACC 100

  Fly   174 --APTTTTTCAPT--TTTTCAPTTTTTCAP---------------TTTTTCAPTTTTTCAPTTTT 219
              :|.....|.|.  .|..|.|   ..|.|               :...|.:|.....|.|   .
Human   101 ASSPCQQACCVPVCCKTVCCKP---VCCVPVCCGDSSCCQQSSCQSACCTSSPCQQACCVP---I 159

  Fly   220 TCAPTTTTTCAPTTTTTCAPTTTTTC--APTTTTTCAPTTTTTCAPTTTTTCAPT--TTTTCAPT 280
            .|.|    .|:..:::.|..::..:|  :|.....|.|   :.|.....::|.|:  ..::|.|.
Human   160 CCKP----VCSGISSSCCQQSSCVSCVSSPCCQAVCEP---SPCQSGCISSCTPSCCQQSSCQPA 217

  Fly   281 TTTT-------CAPT--TTTTCAPTTT---------TTCAPTTTTTCAPTTTTTCAPT--TTTTC 325
            ..|:       |.|.  .|..|.|..:         ::|.|...|: :|.....|.|.  ....|
Human   218 CCTSSSCQQACCVPVCCKTVCCKPVCSEDSSSCCQQSSCQPACCTS-SPCQQACCVPVCCKPVCC 281

  Fly   326 TPGITTTTCTPATTTTCVPET-TTSCASSTTTTE-------CGPVSGV---SGSSKARPSSVKVR 379
            .|..:...|:.|::..|...: ..:|.:|:.:.:       |.|||.|   ||:|.:.......:
Human   282 KPVCSVPICSGASSLCCQQSSCQPACCTSSQSQQGCCVPVCCKPVSCVPVCSGASSSCCQQSSCQ 346

  Fly   380 PARPVRPAVRPALEIDELSAPKAQELTMSTYTKYVCR 416
            ||.......||:..:..|..|             |||
Human   347 PACCTTSCCRPSSSVSLLCRP-------------VCR 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc26B	NP_652552.1	CBM_14	43..86	CDD:426342	7/34 (21%)
		CBM_14	415..463	CDD:426342	2/2 (100%)
KRTAP10-4	NP_941960.2	Keratin_B2	32..165	CDD:366678	37/169 (22%)
		36 X 5 AA repeats of C-C-X(3)	36..395		81/378 (21%)
		Keratin_B2	202..376	CDD:366678	40/183 (22%)