DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc26B and cht-1

DIOPT Version :9

Sequence 1:	NP_652552.1	Gene:	Muc26B / 50424	FlyBaseID:	FBgn0040950	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_508588.1	Gene:	cht-1 / 180628	WormBaseID:	WBGene00000503	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	70/247 - (28%)
Similarity:	99/247 - (40%)	Gaps:	81/247 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 PGSCSQYYECQSGVA--------LVNVCSRFFDAKAQ---------------------------- 83
            |...:||.: ::||.        |.|..:|::|:::|
Worm   322 PAKITQYVQ-EAGVGAYFEFCEMLANGATRYWDSQSQVPYLVQGNQWWSYDDEESFANKMAYVKR 385

  Fly    84 ----GCV-------NYNTGCI----EFQP--ASASSPVGGSIAAVPCAEETTTCAPQIITTTTCT 131
                |..       ::|.||.    :..|  :..:..:||.|  :|.....|| ||..:.||..|
Worm   386 EGYGGAFVWTLDFDDFNAGCSNSNGQLYPLISVIAKELGGVI--IPKKGGVTT-APTTVATTVTT 447

  Fly   132 ---PASVTTTTTCAPTTTTTCAPTTTTTCAPTTTTTCAPTT------TTTCAPTTTTTCAPTTTT 187
               |.:...|||.|.|||||.|.||||.   :.|..|:..:      :..|........:.:.:.
Worm   448 GRPPMTSAVTTTTAATTTTTRAATTTTA---SNTNVCSGKSDGFYPNSNNCGLFVLCLSSKSYSM 509

  Fly   188 TCAP-----------TTTTTCAPTTTTTCAPTTTTTCAPT-TTTTCAPTTTT 227
            :|..           ||:|....:.|||.||||||..||| ||||.||||||
Worm   510 SCPSGLQYSASLKYCTTSTASGCSVTTTRAPTTTTKSAPTVTTTTRAPTTTT 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc26B	NP_652552.1	CBM_14	43..86	CDD:279884	11/70 (16%)
Muc26B	NP_652552.1	CBM_14	415..463	CDD:279884
cht-1	NP_508588.1	GH18_chitolectin_chitotriosidase	55..423	CDD:119351	15/101 (15%)
		Glyco_18	57..399	CDD:214753	11/77 (14%)
		CBM_14	481..532	CDD:279884	6/50 (12%)
		CBM_14	567..615	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900