Protein Alignment PABPC3 and mod

DIOPT Version :10

• Sequence 1: NP_112241.2
• Gene: PABPC3 / 5042
• HGNCID: 8556
• Length: 631
• Species: Homo sapiens
• Sequence 2: NP_524614.2
• Gene: mod / 43764
• FlyBaseID: FBgn0002780
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 417
• Identity: 93/417 - (22%)
• Similarity: 160/417 - (38%)
• Gaps: 81/417 - (19%)

Human    87 SQRDPSLRKSGVGNI----------FVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYG 141
            |:.:..:.|..||.|          ||.||.....:|.|....:.||.:.:.....:.||:|..
  Fly   153 SEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKSV- 216

Human   142 FVHFETHEAAERAIK-KMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDE 205
            .:.|:|...||..:: |...:.|....:.|.|.::::|....         .|.:...|.::..:
  Fly   217 LIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNER---------TVVVGLIGPNITKD 272

Human   206 RLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKV 270
            .||..|.|..|   |:.:|..|.:.....||.....:|..||: :::..||..:.|
  Fly   273 DLKTFFEKVAP---VEAVTISSNRLMPRAFVRLASVDDIPKAL-KLHSTELFSRFI--------- 324

Human   271 ERQTELKRTFEQMKQDRITRYQVVNLYVKNL--DDGIDDERLRKAFSPFGTITSAKVMMEGGRSK 333
                    |..::.|:.|:|...:.|.|:|:  .:....:.|.|.|..||.:....|:.    ||
  Fly   325 --------TVRRISQESISRTSELTLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVC----SK 377

Human   334 G-FGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAY----LTNEYMQRMASVRAVP 393
            . ..||.|...:.||||:.:::|:.|......:...:|....:|.    ||::..:  |.:|.|.
  Fly   378 AVLAFVTFKQSDAATKALAQLDGKTVNKFEWKLHRFERSTSGRAILVTNLTSDATE--ADLRKVF 440

Human   394 N------------QRA-----PPSGY---FMTAVPQTQNHAAYYPPSQIARLRPSPRWTA--QGA 436
            |            |:|     ...|:   |:.......|...:..|:.:.:.|...:..|  |..
  Fly   441 NDSGEIESIIMLGQKAVVKFKDDEGFCKSFLANESIVNNAPIFIEPNSLLKHRLLKKRLAIGQTR 505

Human   437 RPHPFQNKPSAIRPGAPRVPFSTMRPA 463
            .|..||..   .:|...:.||: .|||
  Fly   506 APRKFQKD---TKPNFGKKPFN-KRPA 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC3	NP_112241.2	PABP-1234	11..610	CDD:130689	93/417 (22%)
mod	NP_524614.2	RRM_SF	177..244	CDD:473069	17/67 (25%)
		PABP-1234	262..>470	CDD:130689	52/234 (22%)
		RRM_SF	339..414	CDD:473069	20/78 (26%)