Protein Alignment PABPC3 and Sxl

DIOPT Version :10

• Sequence 1: NP_112241.2
• Gene: PABPC3 / 5042
• HGNCID: 8556
• Length: 631
• Species: Homo sapiens
• Sequence 2: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Alignment Length: 229
• Identity: 68/229 - (29%)
• Similarity: 107/229 - (46%)
• Gaps: 36/229 - (15%)

Human   192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKE 255
            |:.:....:||.|..|..||...||..:.::|.| ::|.|.|:.||.|....|:|:|:..:||..
  Fly   118 NLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGIT 182

Human   256 LNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTI 320
            :..|::.|..|:...|   .:|.|               ||||.||...|.|::|...|..:|:|
  Fly   183 VRNKRLKVSYARPGGE---SIKDT---------------NLYVTNLPRTITDDQLDTIFGKYGSI 229

Human   321 TSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--ATKPLYVALAQRKEERQAYLTNE 381
            ....::.:  .||.:|..||.::..|||.:|::.:|..|.  .::||.|.||:...:.:|   ..
  Fly   230 VQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKA---AH 291

Human   382 YMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAA 415
            :|.:|..|.|  |...||        ||...|.|
  Fly   292 FMSQMGVVPA--NVPPPP--------PQPPAHMA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC3	NP_112241.2	PABP-1234	11..610	CDD:130689	68/229 (30%)
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	58/199 (29%)