Protein Alignment PABPC3 and pAbp

DIOPT Version :9

• Sequence 1: NP_112241.2
• Gene: PABPC3 / 5042
• HGNCID: 8556
• Length: 631
• Species: Homo sapiens
• Sequence 2: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 357/643 - (55%)
• Similarity: 441/643 - (68%)
• Gaps: 50/643 - (7%)

Human    11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFD 75
            ||||||||..||.|:.|::|||.|||:||||:|||:||..|..|||||||...|||.||||||||
  Fly     2 ASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFD 66

Human    76 VIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKG 139
            :::.||:||||||||||||:|||||:|:||||::|:|||:|||.|||||||||.|..||.| |||
  Fly    67 LVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKG 131

Human   140 YGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDD 204
            ||||||||.|||..:|.|:|||||||:||:||:|..|||||.|||.:||.|.|||:|||.||.||
  Fly   132 YGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDD 196

Human   205 ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGKQIYVGRAQK 268
            |:||:.|..:|...|.|||:.|.|||||||||:||..|.|:.||..:|||:: .||.:||.||||
  Fly   197 EKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQK 261

Human   269 KVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMM-EGGRS 332
            |.|||.||||.||::||.|......||||||||||.|||:|||.||||:|.|||||||. |.|||
  Fly   262 KAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRS 326

Human   333 KGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRA------ 391
            ||||||||::..|||.||||:|||:|.:||||||||||||||:|:|.::||:.|..:|.
  Fly   327 KGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQI 391

Human   392 -VPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIA-RLRPSPRWTAQ-------------------- 434
             .||   ..||:|:..:|..|.    :..||:| ::|.:|||..|
  Fly   392 YQPN---AASGFFVPTLPSNQR----FFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGF 449

Human   435 ----GARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAA 495
                ||.|..|::..:..|...|:|  .....|::....:.:|...|.|..||..|......|..
  Fly   450 QGTAGAVPTQFRSAAAGARGAQPQV--QGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQI 512

Human   496 ATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQ--ETLTASRLASAPPQKQKQMLG 558
            |..|.:....|||.:.:|||...:..|.|...|||    ||:  |.|.||.||:|.||:|||:||
  Fly   513 AGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQL----QGKNSEKLIASLLANAKPQEQKQILG 573

Human   559 ERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKE 616
            |||:|:|:.||..||||||||||||:|||||:|:|..|:|::||:|||||||.|:..|
  Fly   574 ERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTE 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC3	NP_112241.2	PABP-1234	11..610	CDD:130689	353/635 (56%)
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	353/635 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I6195
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	703	1.000	Inparanoid score	I670
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm42134
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.840