Protein Alignment PABPC3 and CG12288

DIOPT Version :10

• Sequence 1: NP_112241.2
• Gene: PABPC3 / 5042
• HGNCID: 8556
• Length: 631
• Species: Homo sapiens
• Sequence 2: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 54/226 - (23%)
• Similarity: 95/226 - (42%)
• Gaps: 47/226 - (20%)

Human   174 KSRKEREAELGAR-----AKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGF 233
            |:....:.|.|.:     |:|...|::.|...:....:|..||..:|...|:::.|  :|..:.|
  Fly   133 KANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRT--AGGKQLF 195

Human   234 ------------GFVSFERHEDAQKAVDEMNGKELNGKQIYV---------GRAQKKVERQTELK 277
                        .:|..|:.|.||:|: .:||.|.....:.|         |:|:.|.....:.|
  Fly   196 KHKQRKVAGSLNAYVVLEKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAK 259

Human   278 RTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRS-KGFGFVCFS 341
            ||                ::|.:|.....:|:||:.||..|.|...:.:.:|.:. ||..:|||.
  Fly   260 RT----------------IFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQ 308

Human   342 SPEEATKAVTEMNGRIVATKPLYVALAQRKE 372
            .| :|.....|:|..::..:|:.|...|.|:
  Fly   309 KP-DAVGLALELNQTLLDDRPINVERYQVKK 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC3	NP_112241.2	PABP-1234	11..610	CDD:130689	54/226 (24%)
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	19/83 (23%)
		RRM_SF	261..332	CDD:473069	21/87 (24%)