Protein Alignment schlank and CERS5

DIOPT Version :9

• Sequence 1: NP_652526.1
• Gene: schlank / 50392
• FlyBaseID: FBgn0040918
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_005269277.1
• Gene: CERS5 / 91012
• HGNCID: 23749
• Length: 409
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 162/381 - (42%)
• Similarity: 232/381 - (60%)
• Gaps: 23/381 - (6%)

  Fly    12 WSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRS 76
            ||...|||.|.:|||: .|......:...:.::...|.||.:..||...|||...|....:||..
Human    17 WSERFWLPENVSWADL-EGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCALCIGIED 80

  Fly    77 SRPKKAANVPILEKTYAKSTRL-DKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENT 140
            |.|.:|....||||.:...|:. |||:|..||||.|.:.|:|:.|:|.||.||||.||.||||:.
Human    81 SGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESM 145

  Fly   141 WRCIYYLYSFIFGVIVLWDKPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK 205
            ||..:||..|.:|:..||..|||||::.||:.||.|.:|:.::.||::.::|||||..:||.|:|
Human   146 WRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFYWSLMFSQFTDIK 210

  Fly   206 RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAI 270
            ||||..||:||:||:.|:|.|::.|:.|||:|::.:||.:|..||||||..|||||:|||.:|.|
Human   211 RKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVI 275

  Fly   271 FTVVWIVTRLGFYPRIIYSSSV-EAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQ 334
            |:.|::|||||.||..|.:::: |:..|:..:.::::.|.|||.|.:|||||:|:|.:|.:
Human   276 FSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIAL---- 336

  Fly   335 KGLMSGDIRSSDS------ED---LTDSSGNARLTNGSARSKNKSISSAPSDKGSA 381
            |.|:.|.:|..|.      ||   .||....:.|.       :...||.||.|..|
Human   337 KALIRGKVRMKDGFFLLGMEDRDYSTDVLSPSNLV-------SPIYSSRPSKKPRA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
schlank	NP_652526.1	homeodomain	75..131	CDD:238039	26/56 (46%)
		TLC	135..334	CDD:214789	96/199 (48%)
CERS5	XP_005269277.1	homeodomain	89..136	CDD:238039	23/46 (50%)
		TRAM_LAG1_CLN8	140..333	CDD:281751	95/192 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158721
Domainoid	1	1.000	223	1.000	Domainoid score	I2583
eggNOG	1	0.900	-	-		E1_COG5058
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23634
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2534
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383274at33208
OrthoFinder	1	1.000	-	-		FOG0000327
OrthoInspector	1	1.000	-	-		otm41773
orthoMCL	1	0.900	-	-		OOG6_100372
Panther	1	1.100	-	-	LDO	PTHR12560
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R648
SonicParanoid	1	1.000	-	-		X237
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.830