Protein Alignment schlank and Cers4

DIOPT Version :10

• Sequence 1: NP_652526.1
• Gene: schlank / 50392
• FlyBaseID: FBgn0040918
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_080334.3
• Gene: Cers4 / 67260
• MGIID: 1914510
• Length: 393
• Species: Mus musculus
• Alignment Length: 380
• Identity: 143/380 - (37%)
• Similarity: 227/380 - (59%)
• Gaps: 8/380 - (2%)

  Fly     8 SNVFWSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSL 72
            |...|....|||||.|||::.  .|..:|.|:...::...|.|.|::.||...|||...|:.:.:
Mouse     6 SEWLWQETYWLPPNVTWAELE--DRDGLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWM 68

  Fly    73 GIRSSRPKKAANVPILEKTYAKSTRL-DKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKF 136
            |::....:|....|:|||.:.:..:. ::.::|.|:.|..::.|:.:||:|.||.||:||...||
Mouse    69 GVQDPIRRKIKPNPVLEKYFLRMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKF 133

  Fly   137 CENTWRCIYYLYSFIFGVIVLWDKPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQF 201
            ||..||.::||.||:.|..:|:.:.|.|....||..||||:::..::|:|::.:.||.||..|..
Mouse   134 CEACWRFVFYLCSFVGGTSILYHESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLP 198

  Fly   202 FDVKRKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDA 266
            ||||||||.:..:||.|.:.|:..|:..||.|:|::||::|||:|..||..|:..||.:::.|||
Mouse   199 FDVKRKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDA 263

  Fly   267 IFAIFTVVWIVTRLGFYP-RIIYSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVV 330
            :|.:|.:|:..|||.|:| ::||:|..::.:....|..||.|..||:||.:|||.|..:||:::.
Mouse   264 LFIMFALVFFYTRLIFFPTQVIYTSVYDSIKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLY 328

  Fly   331 DSLQKGLMSGDIRSS----DSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSA 381
            ..|.||.|:.||||.    ||.|....|...:|.||.||....::::.|..:.:|
Mouse   329 SFLHKGQMTEDIRSDVEEPDSSDDEPVSEGPQLKNGMARGSRVAVTNGPRSRAAA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
schlank	NP_652526.1	homeodomain	75..131	CDD:238039	16/56 (29%)
		TLC	135..334	CDD:214789	83/199 (42%)
Cers4	NP_080334.3	Homeobox-like. /evidence=ECO:0000305	67..128		17/60 (28%)
		homeodomain	<83..128	CDD:238039	14/44 (32%)
		TLC	131..332	CDD:214789	83/200 (42%)
		Last loop motif. /evidence=ECO:0000250|UniProtKB:Q9HA82	291..301		1/9 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..393		13/43 (30%)