Protein Alignment schlank and CERS1

DIOPT Version :9

• Sequence 1: NP_652526.1
• Gene: schlank / 50392
• FlyBaseID: FBgn0040918
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_001374368.1
• Gene: CERS1 / 10715
• HGNCID: 14253
• Length: 363
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 86/288 - (29%)
• Similarity: 139/288 - (48%)
• Gaps: 39/288 - (13%)

  Fly   120 WWRLRRAQD-------------KPSTLVKFCENTWRCIYYLYSFIFGVIVLW--DKPWFWDVKSC 169
            |..||.|..             :|....|..|:.|:.::||.|:.:...:|:  |.|:|.|..|.
Human    70 WTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSV 134

  Fly   170 WYGY-PHQSISNDIWWYYMISMSFY-WSLTGTQFFDVKRKDFWQMFIHHMVTLLLMSLSWVCNLH 232
            :|.: |..::..||...|::..||| .|:..|.:.|..|||...|.:||:|||:|:..|:....|
Human   135 FYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYH 199

  Fly   233 RVGSLVLVVHDCADIFLEAAKLTKYAK-----YQKL----CDAIFAIFTVVWIVTRLGFYP-RII 287
            .||.|||.:||.:|:.||..||..|.|     |.:|    .|.....|...|...||.::| :::
Human   200 NVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVL 264

  Fly   288 YSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMIL----KIVVDSLQ--KGLMSGD----- 341
            |::|..:.|.:|..|.|:.||:|||:|.::::.|...|:    |::...:.  |.|...|
Human   265 YATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQVHELKDLREYDTAEAQ 329

  Fly   342 -IRSSDSEDLTDSSGNARLTNGSARSKN 368
             ::.|.:|:....|.......|.||.::
Human   330 SLKPSKAEEAVAQSSVTFFGTGGARCRH 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
schlank	NP_652526.1	homeodomain	75..131	CDD:238039	4/23 (17%)
		TLC	135..334	CDD:214789	72/216 (33%)
CERS1	NP_001374368.1	TLC	98..311	CDD:214789	72/212 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R648
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940