Sequence 1: | NP_572285.2 | Gene: | Grip / 50391 | FlyBaseID: | FBgn0029830 | Length: | 1058 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001119800.1 | Gene: | LNX1 / 84708 | HGNCID: | 6657 | Length: | 728 | Species: | Homo sapiens |
Alignment Length: | 709 | Identity: | 162/709 - (22%) |
---|---|---|---|
Similarity: | 252/709 - (35%) | Gaps: | 205/709 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 44 HHPPTDTALAPM--LSVDRAMSPAQSEDSGLAPERGTTYATITLPRNALHLAITFAERND---LS 103
Fly 104 YPPVVGS-------LNPV--GHAADFLA-PGDRLHQIDGISTIGLSNQKVMNMLC-------AGG 151
Fly 152 SDACPAIVEIEYS----LPECTVSQNSLCVTSKLAQITVER--ESGCLGLTLRGGADYPL---IV 207
Fly 208 THVRPHGPVYKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSV 272
Fly 273 EF-----SMGPLLIEIERPMNDKLGLVLCNYTAAVPASGSGSSTPSSG------EKIEESAGVFI 326
Fly 327 ASILPASIADRCGALSVGDQVLSIDDTMIEHTAFSPDEVMTILDTSTGRGYTQMQIMPAHALARR 391
Fly 392 GHTTLGSPKYSFSTLESRKSSTAGRQR-----QRFARKSSLPLENPACGTPGSTGGSMGTGGIHG 451
Fly 452 SSSLGMGLGLCRAESFPVLLDCSHGAGIILSETVSGSGGSG-----AVAIAQIVPDSVADRSGCI 511
Fly 512 QAGD----------------RIVAINKMYS----LDAAAMRQ-----------LLEGGSSRNGAS 545
Fly 546 NGTPA--NWLELEIEFDMPDAVVPASGVFSVKLLRAGKCG-LGLSVSG--SSHGG---LVISDVK 602
Fly 603 MGSPAHRSGSLRSGDILLAVDQHPVQ---HFNVDALLKE-EGRSQNPSHSSSDFTTLTI 657 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Grip | NP_572285.2 | PDZ | 82..147 | CDD:294084 | 21/77 (27%) |
PDZ_signaling | 183..254 | CDD:238492 | 20/75 (27%) | ||
PDZ_signaling | 278..375 | CDD:238492 | 25/102 (25%) | ||
PDZ | 496..>521 | CDD:294084 | 9/40 (23%) | ||
PDZ_signaling | 571..658 | CDD:238492 | 31/97 (32%) | ||
PDZ_signaling | 832..913 | CDD:238492 | |||
PDZ_signaling | 973..1055 | CDD:238492 | |||
LNX1 | NP_001119800.1 | mRING-HC-C3HC3D_LNX1 | 38..79 | CDD:319693 | |
modified RING-HC finger (C3HC3D-type) | 41..78 | CDD:319693 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 178..214 | 10/42 (24%) | |||
NPXY motif | 181..184 | 1/2 (50%) | |||
Interaction with MAGEB18. /evidence=ECO:0000269|PubMed:20864041 | 186..244 | 14/64 (22%) | |||
PDZ_signaling | 272..355 | CDD:238492 | 22/91 (24%) | ||
PDZ_signaling | 380..460 | CDD:238492 | 24/110 (22%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..494 | 4/24 (17%) | |||
PDZ_signaling | 505..588 | CDD:238492 | 18/87 (21%) | ||
PDZ_signaling | 637..721 | CDD:238492 | 31/99 (31%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3528 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |