DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and GOPC

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:NP_065132.1 Gene:GOPC / 57120 HGNCID:17643 Length:462 Species:Homo sapiens


Alignment Length:318 Identity:67/318 - (21%)
Similarity:117/318 - (36%) Gaps:70/318 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   695 HDLYSSAYVTAGKYADCVSLKSRTPQP---------DYFRVPSMDDASLQS-VQLRSGSGSNGGN 749
            |.:....:...|:.||..::|::...|         :..:...|.:|.|:: |:|....     |
Human   127 HSIQLQLHAKTGQSADSGTIKAKLSGPSVEELERELEANKKEKMKEAQLEAEVKLLRKE-----N 186

  Fly   750 QAANSWSTGVNSRSYVAPPNTQSLTTEL----------------PEEEDEQEQMYPGYELNRYAS 798
            :|.......:.:..|.|....:.|..||                |..:....|:.....|:|:.:
Human   187 EALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKT 251

  Fly   799 V--DCTA---LPPPMENKVYGSAASSSSKSSGSSLHQIIFTVRLEPKGGLLGITLAGSEDITKSI 858
            |  .|..   |..||:... |....|..||.|....:.:..::.:.:|  |||::.|.::....|
Human   252 VIRACRGRNDLKRPMQAPP-GHDQDSLKKSQGVGPIRKVLLLKEDHEG--LGISITGGKEHGVPI 313

  Fly   859 TISGLVEGGIAHKNGQIHVGDQLLAIDEHSVQGMPLSHATSLL-QNLGDLVDLKILRSHDLANGS 922
            .||.:..|..|.:.|.:||||.:||::..:::......|.::| |..|::               
Human   314 LISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEI--------------- 363

  Fly   923 HLPQTQAIYAKVQRRPRSPSANTEASKESG----------SGNANGGGAVNGNSGSGK 970
               :.:.:|  |.....|...|.|...|||          .|..|.|.:....||..|
Human   364 ---EFEVVY--VAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCKDTSGEIK 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492
PDZ_signaling 278..375 CDD:238492
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492 21/81 (26%)
PDZ_signaling 973..1055 CDD:238492
GOPCNP_065132.1 bZIP_2 <166..199 CDD:285017 7/37 (19%)
PDZ_signaling 286..368 CDD:238492 21/101 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 426..449
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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