DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and Tamalin

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:NP_062391.3 Gene:Tamalin / 56149 MGIID:1860303 Length:392 Species:Mus musculus


Alignment Length:284 Identity:63/284 - (22%)
Similarity:99/284 - (34%) Gaps:84/284 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   207 VTHVRPHGPVYKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIE--YDVSV- 268
            |..|....|....| :.|||.:..|:.:::.|....|...|||..|:|     |.:|  |..|: 
Mouse   134 VCRVHESSPAQLAG-LTPGDTIASVNGLNVEGIRHREIVDIIKASGNV-----LRLETLYGTSIR 192

  Fly   269 -----------VQSVEFSMG---PLLIEIERPMNDKLGLVLCNYTAAVPASGSGSSTPSSGEKIE 319
                       .|::....|   .|:::.:|.::   |||:              ..||..:.:|
Mouse   193 KAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVH---GLVV--------------KDPSIYDTLE 240

  Fly   320 E-SAGVFIASILPASI----------ADRCGA-LSVGDQVLSIDDTMIEHTAFSPDEVMTILDTS 372
            . .:.::.|.:||.|:          :.|.|| .:.||     .|..:.||.|.           
Mouse   241 SVRSCLYGAGLLPGSLPFGPLLAAPGSARGGARRAKGD-----TDDAVYHTCFF----------- 289

  Fly   373 TGRGYTQMQIMPAHALARRGHTTLGSPKYSFSTLESRKSSTAGRQRQRFARKSSLPLENPACGTP 437
               |..:.|.:|......|   .||.     |:.|:..|......|...:|.:|:     .|..|
Mouse   290 ---GGAEPQALPPPPPPAR---ALGP-----SSAETPASVLFPAPRSTLSRSASV-----RCAGP 338

  Fly   438 GSTGGSMGTGGIHGSSSLGMGLGL 461
            |..||:.|............|.||
Mouse   339 GGGGGAPGALWTEAREQALCGAGL 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492 14/46 (30%)
PDZ_signaling 278..375 CDD:238492 21/108 (19%)
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492
PDZ_signaling 973..1055 CDD:238492
TamalinNP_062391.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50
PDZ_signaling 99..184 CDD:238492 16/55 (29%)
Interaction with PSCD3. /evidence=ECO:0000269|PubMed:10828067 180..257 19/98 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..315 7/28 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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