DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and PDZD11

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:XP_016885057.1 Gene:PDZD11 / 51248 HGNCID:28034 Length:172 Species:Homo sapiens


Alignment Length:174 Identity:39/174 - (22%)
Similarity:63/174 - (36%) Gaps:68/174 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   202 DYPLIVTHVRPHGPVYKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDV 266
            |||::......:.|.:    |.|.:|:                        |...|.|       
Human    41 DYPVVFLPAYENPPAW----IPPHERV------------------------HHPDYNN------- 70

  Fly   267 SVVQSVEFSMGPLLIEIERPMNDKLGLVLCNYTAAVPASGSGSSTPSSGEKIEESAGVFIASILP 331
               :..:|.  |..|.:::|...:||..:        ..|..|           ..|:||:.::|
Human    71 ---ELTQFL--PRTITLKKPPGAQLGFNI--------RGGKAS-----------QLGIFISKVIP 111

  Fly   332 ASIADRCGALSVGDQVLSIDDT---MIEHTAFSPDEVMTILDTS 372
            .|.|.|.| |..|||||:::|.   .|||:     :.:.||.|:
Human   112 DSDAHRAG-LQEGDQVLAVNDVDFQDIEHS-----KAVEILKTA 149

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492 7/51 (14%)
PDZ_signaling 278..375 CDD:238492 28/98 (29%)
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492
PDZ_signaling 973..1055 CDD:238492
PDZD11XP_016885057.1 PDZ_signaling 77..157 CDD:238492 28/98 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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