DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and gopc

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:NP_956851.1 Gene:gopc / 326887 ZFINID:ZDB-GENE-030131-5086 Length:455 Species:Danio rerio


Alignment Length:476 Identity:93/476 - (19%)
Similarity:157/476 - (32%) Gaps:154/476 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   579 AGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRSGDILLAV--DQHPVQHFNVDALLKE--- 638
            ||..|.|||                ..||..:||..|....|.|  .:......:||.||.|   
Zfish     8 AGSPGSGLS----------------AGPAAATGSGMSMFRWLEVLEKEFDKAFVDVDLLLGEIDP 56

  Fly   639 -------EGRSQNPSHSS---------------------------SDFTTLTIKRIVLPDFLPMS 669
                   |||.:..|.||                           |:.|.:..:::|      :.
Zfish    57 DQADITYEGRQKMTSLSSCFAQLCHKAQTIFQLNHKLEAQLVDLRSELTDVQAEKVV------VE 115

  Fly   670 SPIYSNCPASGINLGMGMGVSTSTDHDLYSSAYVTAGKYADCVSLKSRTPQPDYFRVPSMDD--- 731
            ..::...    :.|           |.:........|:..|..|:|.|.|      |||:::   
Zfish   116 KEVHEQL----LQL-----------HAMQLKLQAKGGQAVDSDSIKDRMP------VPSVEEKEK 159

  Fly   732 -------ASLQSVQLRSG-SGSNGGNQAANSWSTGVNSRSYVAPPNTQSLTTEL----------- 777
                   ..::.|:|.:. ......|:|.......:.:..|.|....:.|..||           
Zfish   160 ELEASKKEKVKEVKLEAEVKMLKKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLG 224

  Fly   778 -----PEEEDEQEQMYPGYELNRYASV--DCTA-------LPPPMENKVYGSAASSSSKSSG-SS 827
                 |..:....|:.....|:|:.:|  .|..       ||.|:     |....|..|:.| ..
Zfish   225 RDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDPKKPLPSPV-----GHDTDSLKKTQGVGP 284

  Fly   828 LHQIIFTVRLEPKGGLLGITLAGSEDITKSITISGLVEGGIAHKNGQIHVGDQLLAIDEHSVQGM 892
            :.:::.| :.:.:|  |||::.|.::....|.||.:.....|.:.|.:||||.:||::..:::..
Zfish   285 IRKVVLT-KEDHEG--LGISITGGKEHGVPILISEIHPTQPAERCGGLHVGDAILAVNNINLRDA 346

  Fly   893 PLSHATSLL-QNLGDLVDLKILRSHDLANGSHLPQTQAIYAKVQRRPRSPSANTEASKESGS--- 953
            ....|.::| |..|::                  :.:.:|  |.....|...|.|...:||.   
Zfish   347 KHKEAVTILSQQRGEI------------------EFEVVY--VAPEVDSDDENVEYEDDSGHRYR 391

  Fly   954 ---GNANGGGAVNGNSGSGKP 971
               .......|.|.|:|:..|
Zfish   392 LYLDELEEASAANHNNGTADP 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492
PDZ_signaling 278..375 CDD:238492
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492 26/117 (22%)
PDZ_signaling 832..913 CDD:238492 21/81 (26%)
PDZ_signaling 973..1055 CDD:238492
gopcNP_956851.1 PDZ_signaling 285..367 CDD:238492 21/102 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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