DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and Ptpn14

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:XP_008768075.1 Gene:Ptpn14 / 305064 RGDID:1307885 Length:1189 Species:Rattus norvegicus


Alignment Length:434 Identity:79/434 - (18%)
Similarity:141/434 - (32%) Gaps:128/434 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   525 SLDAAAMRQLLEGGSSRNGASNGTPANWLELEIEFDMPDAVVPASG----VFSVKLLRAGKCGLG 585
            :::.||:.:|.:..:..:.|.:|.    |..|.|....:.|....|    :|.||........||
  Rat   173 AMEEAALEELTQKVAQEHKAHSGI----LPAEAELMYINEVERLDGFGQEIFPVKDSHGNSMHLG 233

  Fly   586 LSVSG------SSHGGLVISDVKMGSPAHRSGSLRSGDILLAVDQHPVQHFNVDALLKEEGRSQN 644
            :...|      .....::.....:|:..|...::    :|..:|:.....|:.|.:       :|
  Rat   234 IFFMGIFVRNRIGRQAVIYRWNDIGTVTHSKAAI----LLELIDKEETALFHTDDI-------EN 287

  Fly   645 PSHSSSDFTTLTIKRIVLPDFLPMSSPIYSNCPASGINLGMGMGVSTSTDHDLYSSAYVTAGKYA 709
            ..:.|..||                                       |.|..|....:      
  Rat   288 AKYISRLFT---------------------------------------TRHKFYKQNKI------ 307

  Fly   710 DCVSLKSRTPQPDYFRVPSMDDASLQSVQLRSGSGSNGGNQAANSWSTGVNSRSYVAPPNTQSLT 774
             |.. :|.:| |...|.|:...:||...|                        .|:.||.....:
  Rat   308 -CTE-QSNSP-PPIRRQPTWSRSSLPRQQ------------------------PYILPPMHVQCS 345

  Fly   775 TELPEEEDEQEQMYPGYE----LNRYASVDCTALPPPMENKVYGSAASSSSKSSGSSLHQIIFTV 835
            ....|....|:.::||.|    .|.:.|:|...|...:.|....|..|.:|.|...|.      :
  Rat   346 EHYSETHTSQDSIFPGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSINSLSCSQSF------I 404

  Fly   836 RLEPKGGLLGITLAGSEDITKSITISGLVEGGIAHKNGQIHVGDQLLAIDEHSVQGM---PLSHA 897
            :..|...  .:::.|| ||.::..|.       :|::..|.|.......|..:|...   .|.||
  Rat   405 QASPVSS--NLSIPGS-DIMRADYIP-------SHRHSTIIVPSYRPTPDYETVMRQMKRGLLHA 459

  Fly   898 TSLLQNLGDLVDLKILRSHDLANGSHLPQTQAIYAKVQRRPRSP 941
            .|..::|.   :|.|:.:|     ::....:.:|::.:.|.|.|
  Rat   460 DSQSRSLR---NLNIINTH-----AYNQPEELVYSQPEMRERHP 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492
PDZ_signaling 278..375 CDD:238492
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492 16/92 (17%)
PDZ_signaling 832..913 CDD:238492 17/83 (20%)
PDZ_signaling 973..1055 CDD:238492
Ptpn14XP_008768075.1 B41 24..220 CDD:214604 10/50 (20%)
PH-like 215..305 CDD:418428 19/139 (14%)
PTPc-N14 898..1184 CDD:350447
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0792
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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