DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and SCRIB

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:NP_874365.3 Gene:SCRIB / 23513 HGNCID:30377 Length:1655 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492
PDZ_signaling 278..375 CDD:238492
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492
PDZ_signaling 973..1055 CDD:238492
SCRIBNP_874365.3 Sufficient for targeting to adherens junction and to inhibit cell proliferation 1..818
LRR_RI 12..232 CDD:238064
leucine-rich repeat 14..37 CDD:275380
leucine-rich repeat 38..60 CDD:275380
LRR 39..401 CDD:227223
leucine-rich repeat 61..83 CDD:275380
leucine-rich repeat 84..106 CDD:275380
leucine-rich repeat 107..129 CDD:275380
leucine-rich repeat 130..152 CDD:275380
leucine-rich repeat 153..175 CDD:275380
leucine-rich repeat 176..198 CDD:275380
leucine-rich repeat 199..221 CDD:275380
leucine-rich repeat 268..290 CDD:275380
leucine-rich repeat 291..313 CDD:275380
leucine-rich repeat 314..336 CDD:275380
leucine-rich repeat 360..381 CDD:275380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 417..440
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 459..604
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 633..702
Interaction with ARHGEF7. /evidence=ECO:0000269|PubMed:15182672 717..1229
PDZ 725..813 CDD:214570
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 827..853
PDZ_signaling 860..947 CDD:238492
PDZ_signaling 1002..1090 CDD:238492
PDZ_signaling 1098..1189 CDD:238492
Interaction with tick-borne encephalitis virus RNA-directed RNA polymerase NS5. /evidence=ECO:0000269|PubMed:18042258 1105..1117
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1227..1246
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1277..1489
AbLIM_anchor 1555..>1593 CDD:292800
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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