DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and F28E10.4

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:NP_500590.2 Gene:F28E10.4 / 185067 WormBaseID:WBGene00017902 Length:324 Species:Caenorhabditis elegans


Alignment Length:300 Identity:64/300 - (21%)
Similarity:108/300 - (36%) Gaps:73/300 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 GDRLLRVDNVSLIGKTLAEAQQIIK---CGGHVS---GYTNLTIEYDVSVVQSVEFSMGPLLIEI 283
            ||:::||:|||  |.......::::   |...||   |.|.:|.|.......::.......::::
 Worm    61 GDKIIRVNNVS--GSASRCQSELLRGTACNVEVSRRKGVTPVTCERLAKSGCNLRKGHACFVLDV 123

  Fly   284 ERP-------MNDKLGLVLCN-YTAAVPASGSGSSTPSSGEKIEESAGVFIASILPAS------I 334
            |||       :..|||::... :...|..:...||....|:.|.:.:|    :.:|.:      |
 Worm   124 ERPPHMTTTSVGLKLGIIKRRAFVTKVDPNTIASSFFGCGDSIMDMSG----APIPMTDNPDNFI 184

  Fly   335 ADRCGALSVGDQV-------LSID-----DTMIEHTAFSPDEVMTILDT-STGRGYTQMQIMPAH 386
            .:....||.|.:|       :|:.     ...||...:...||....|. ..||..:.|..|...
 Worm   185 REHLSRLSTGAKVSFLVERPISVAMAKQYQKFIESITYDDSEVEMAQDVIEIGREASNMHFMILK 249

  Fly   387 ALARRGHTTLGSPKYSFSTLESRKSSTAGRQRQRFARKSSLPLENPACGTPGSTGGSMGTGGIHG 451
            .|.        :|....|.:..||.|.         .|:|           .||.||:....  .
 Worm   250 KLV--------TPSILSSDVRRRKKSN---------NKTS-----------ESTEGSITISS--A 284

  Fly   452 SSSLGMGLGLCRAESFPVLLDCSHGAGIILSETVSGSGGS 491
            |:.:.:...:...:....:...||.||    .:.|.|||:
 Worm   285 STEMKITSDVTDFDDLKPVESKSHAAG----SSSSDSGGA 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492 9/31 (29%)
PDZ_signaling 278..375 CDD:238492 24/123 (20%)
PDZ 496..>521 CDD:294084
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492
PDZ_signaling 973..1055 CDD:238492
F28E10.4NP_500590.2 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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